A Promising Drug Target: FOCAD (KIAA1797) (G54914)
A Promising Drug Target: FOCAD (KIAA1797)
FOCAD (KiAA1797) is a protein that is expressed in most tissues of the body. Its full name is K-type ATP-binding cassette subfamily A member 1797. FOCAD is a protein that is known for its role in various cellular processes. It is a potential drug target due to its unique structure and the diseases it is associated with. In this article, we will discuss the FOCAD protein, its function, potential drug targets, and its potential as a biomarker.
FOCAD Protein
FOCAD is a protein that is expressed in most tissues of the body. It is a member of the K-type ATP-binding cassette subfamily A (KABCA) family. This family is known for its role in intracellular signaling pathways. FOCAD is a 21 kDa protein that consists of 216 amino acids. It has a unique structure that is composed of a catalytic domain, a transmembrane region, and an extracellular domain.
FOCAD Functions
FOCAD is involved in various cellular processes, including intracellular signaling pathways, cell adhesion, and neurotransmission. It is a key protein that is involved in the regulation of the calcium ions in the cell. FOCAD is also involved in the regulation of the levels of phosphatidylinositol (PI) in the cell, which is a signaling molecule that is involved in various cellular processes.
FOCAD as a Drug Target
FOCAD is a potential drug target due to its unique structure and the diseases it is associated with. One of the diseases associated with FOCAD is cancer. Cancer is a disease that is characterized by the formation of tumors. FOCAD has been shown to be involved in the regulation of cell division and has been linked to the development and progression of various types of cancer.
FOCAD has also been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels form in the body. This is important for the development of tumors and other diseases.
FOCAD as a Biomarker
FOCAD has also been shown to be involved in the regulation of various signaling pathways in the body. This makes it an attractive biomarker for the diagnosis and treatment of various diseases. For example, FOCAD has been shown to be involved in the regulation of the production of reactive oxygen species (ROS), which are free radicals that can cause damage to cellular components.
FOCAD has also been shown to be involved in the regulation of the production of endoplasmic reticulum-associated degradation (ER-associated degradation) products, which are proteins that are involved in the degradation of cellular components. This is important for the diagnosis and treatment of various diseases, including cancer.
Conclusion
FOCAD is a protein that is involved in various cellular processes and has been linked to the development and progression of various diseases. Its unique structure and involvement in intracellular signaling pathways make it an attractive drug target. As a potential biomarker, FOCAD has the potential to revolutionize the diagnosis and treatment of various diseases. Further research is needed to fully understand the role of FOCAD in cellular processes and its potential as a drug target and biomarker.
Protein Name: Focadhesin
Functions: Required for the maintenance of SKIC2 and SKIC3 proteostatic levels in the liver. May be involved in the regulation of RNA degradation by the exosome complex (PubMed:35864190). Potential tumor suppressor in gliomas
More Common Targets
Focal Adhesion Kinases (FAK) | Folate Receptor | FOLH1 | FOLH1B | Follicle stimulating hormone | FOLR1 | FOLR2 | FOLR3 | Formin homology 2 domain-containing proteins | FOS | FOSB | FOSL1 | FOSL2 | FOSL2-AS1 | FOXA1 | FOXA2 | FOXA3 | FOXB1 | FOXB2 | FOXC1 | FOXC2 | FOXC2-AS1 | FOXCUT | FOXD1 | FOXD2 | FOXD2-AS1 | FOXD3 | FOXD3-AS1 | FOXD4 | FOXD4L1 | FOXD4L3 | FOXD4L4 | FOXD4L5 | FOXD4L6 | FOXE1 | FOXE3 | FOXF1 | FOXF2 | FOXF2-DT | FOXG1 | FOXG1-AS1 | FOXH1 | FOXI1 | FOXI2 | FOXI3 | FOXJ1 | FOXJ2 | FOXJ3 | FOXK1 | FOXK2 | FOXL1 | FOXL2 | FOXL2NB | FOXL3-OT1 | FOXM1 | FOXN1 | FOXN2 | FOXN3 | FOXN3-AS1 | FOXN3-AS2 | FOXN4 | FOXO1 | FOXO1B | FOXO3 | FOXO3B | FOXO4 | FOXO6 | FOXO6-AS1 | FOXP1 | FOXP2 | FOXP3 | FOXP4 | FOXP4-AS1 | FOXQ1 | FOXR1 | FOXR2 | FOXRED1 | FOXRED2 | FOXS1 | FP588 | FPGS | FPGT | FPGT-TNNI3K | FPR1 | FPR2 | FPR3 | FRA10AC1 | FRAS1 | FRAT1 | FRAT2 | FREM1 | FREM2 | FREM3 | FREY1 | FRG1 | FRG1-DT | FRG1BP | FRG1FP | FRG1GP | FRG1HP