MATE-1: A Protein with Potential as A Drug Target Or Biomarker

Target Name: SLC47A1

NCBI ID: G55244

MATE-1: A Protein with Potential as A Drug Target Or Biomarker

SLC47A1 (MATE-1) is a gene that encodes a protein known as MATE-1. MATE-1 is a member of the MATE family of proteins, which are involved in the regulation of various cellular processes, including cell signaling, DNA replication, and metabolism. The MATE-1 protein has been shown to play a role in a variety of cellular processes, including the regulation of cell growth, the development of cancer, and the regulation of pain.

One of the unique features of MATE-1 is its ability to interact with other proteins, including the protein SLC47A2. SLC47A2 is a zinc transporter that is involved in the regulation of various cellular processes, including cell signaling and DNA replication. The interaction between MATE-1 and SLC47A2 has been shown to play a role in the regulation of cell growth, cell division, and the development of cancer.

In addition to its role in cell signaling and development, MATE-1 has also been shown to play a role in the regulation of pain. MATE-1 has been shown to interact with a protein called TrPV1, which is involved in the regulation of pain sensitivity. The interaction between MATE-1 and TrPV1 has been shown to play a role in the regulation of pain sensitivity and the development of chronic pain.

Despite its many functions, MATE-1 is still an relatively unexplored protein. There is currently limited research on the biology and chemistry of MATE-1, and much of its behavior and function remain unknown. However, the potential implications of MATE-1 as a drug target or biomarker are significant.

MATE-1 has been shown to play a role in the regulation of various cellular processes, including cell growth, cell division, and the development of cancer. It has also been shown to play a role in the regulation of pain sensitivity and the development of chronic pain. The interaction between MATE-1 and SLC47A2 has been shown to play a role in these processes, and the regulation of MATE-1 by SLC47A2 may be a potential target for drug development.

In addition to its potential as a drug target, MATE-1 may also be a useful biomarker for certain diseases. The regulation of MATE-1 by SLC47A2 has been shown to play a role in the development of various diseases, including cancer, neurodegenerative diseases, and chronic pain. Therefore, the regulation of MATE-1 by SLC47A2 may be a useful biomarker for these diseases, and may also be a potential target for drug development.

Overall, MATE-1 is a protein that has significant potential as a drug target or biomarker. The regulation of MATE-1 by SLC47A2 has been shown to play a role in various cellular processes, including cell growth, cell division, and the development of cancer, as well as the regulation of pain sensitivity and the development of chronic pain. Further research is needed to fully understand the behavior and function of MATE-1, and to explore its potential as a drug target or biomarker.

Protein Name: Solute Carrier Family 47 Member 1

Functions: Multidrug efflux pump that functions as a H(+)/organic cation antiporter (PubMed:16330770, PubMed:17509534). Plays a physiological role in the excretion of cationic compounds including endogenous metabolites, drugs, toxins through the kidney and liver, into urine and bile respectively (PubMed:16330770, PubMed:17495125, PubMed:17509534, PubMed:17582384, PubMed:18305230, PubMed:19158817, PubMed:21128598, PubMed:24961373). Mediates the efflux of endogenous compounds such as creatinine, vitamin B1/thiamine, agmatine and estrone-3-sulfate (PubMed:16330770, PubMed:17495125, PubMed:17509534, PubMed:17582384, PubMed:18305230, PubMed:19158817, PubMed:21128598, PubMed:24961373). May also contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (Probable)

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