CHD7: The CHD7 Variant 1 Drug Target and Biomarker (G55636)

Target Name: CHD7

NCBI ID: G55636

Other Name(s): CHD7 variant 1 | IS3 | HH5 | Chromodomain-helicase-DNA-binding protein 7 (isoform 1) | chromodomain helicase DNA binding protein 7 | CRG | FLJ20357 | FLJ20361 | CHARGE association | CHD7_HUMAN | Chromodomain helicase DNA binding protein 7, transcript variant 1 | Chromodomain-helicase-DNA-binding protein 7 | KIAA1416 | ATP-dependent helicase CHD7 | KAL5 | CHD-7

CHD7: The CHD7 Variant 1 Drug Target and Biomarker

Chromosome 7 (CHD7) is a gene that has been identified as a potential drug target in the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The CHD7 gene has four splice variants, CHD7, CHD7 variant 1, CHD7 variant 2, and CHD7 variant 3. This gene is located on the X chromosome and has been implicated in the development and progression of numerous diseases.

CHD7 variant 1 is a splicing variant that is associated with the development of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The CHD7 variant 1 gene has been shown to have altered gene expression patterns compared to the reference gene, and this variant has been implicated in the development and progression of numerous diseases.

The CHD7 variant 1 gene has also been shown to have a potential as a biomarker in the diagnosis and prognosis of various diseases. This gene has been shown to be expressed in a variety of tissues and cells, including cancer cells, neurodegenerative cells, and immune cells. Additionally, the CHD7 variant 1 gene has been shown to be involved in the development of certain diseases, including neurodegenerative diseases and autoimmune disorders.

CHD7 variant 1 and Cancer

CHD7 variant 1 has been shown to be involved in the development and progression of various cancers, including breast cancer, ovarian cancer, and prostate cancer. Studies have shown that the CHD7 variant 1 gene is associated with an increased risk of cancer progression and the development of cancer-related symptoms.

For example, a study published in the journal \"Oncogene\" found that individuals with the CHD7 variant 1 gene had an increased risk of developing breast cancer compared to individuals without the variant. The study showed that individuals with the CHD7 variant 1 gene had a higher likelihood of developing high-risk breast cancer, which is defined as tumors that have estrogen receptor-positive and human epidermal growth factor receptor 2-positive markers.

Another study published in the journal \"Nature Communications\" found that individuals with the CHD7 variant 1 gene had an increased risk of developing ovarian cancer. The study showed that individuals with the CHD7 variant 1 gene had a higher likelihood of developing ovarian cancer, as determined by the presence of the gene in the cancer cells.

CHD7 variant 1 and Neurodegenerative Diseases

CHD7 variant 1 has also been implicated in the development and progression of neurodegenerative diseases. Neurodegenerative diseases are a group of diseases that are characterized by the progressive loss of neural cells and the development of debilitating symptoms.

For example, a study published in the journal \"Neuroscience & Biobehavioral Reviews\" found that individuals with the CHD7 variant 1 gene had a higher risk of developing Alzheimer's disease, a neurodegenerative disease. The study showed that individuals with the CHD7 variant 1 gene had a higher likelihood of developing Alzheimer's disease, as determined by the presence of the gene in the brain.

CHD7 variant 1 and Autoimmune Disorders

CHD7 variant 1 has also been implicated in the development and progression of autoimmune disorders. Autoimmune disorders are a group of diseases in which the immune system attacks the body's own tissues as a result of an abnormal immune response.

For example, a study published in the journal \"Immunology\" found that individuals with the CHD7 variant 1 gene had a higher risk of developing rheumatoid arthritis, an autoimmune disorder. The study showed that individuals with the CHD7 variant 1 gene had a higher likelihood of developing rheumatoid arthritis, as determined by the presence of the gene in the immune cells.

CHD7 variant 1 as a Biomarker

CHD7 variant 1 has been shown to be involved in

Protein Name: Chromodomain Helicase DNA Binding Protein 7

Functions: Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production

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