CHST11: A Potential Drug Target in Intracellular Signaling (G50515)

Target Name: CHST11

NCBI ID: G50515

CHST11: A Potential Drug Target in Intracellular Signaling

CHST11 (HSA269537) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the CHST (chaperone histidine-containing proteins) family, which are known for their ability to interact with nucleotides and other small molecules.

One of the key functions of CHST11 is its role in intracellular signaling. It is a protein that can interact with various signaling molecules, including histidine, which is a nucleotide that plays a crucial role in many cellular processes.

CHST11 has been shown to be involved in a number of different signaling pathways, including the regulation of cell growth, the development of tissues, and the regulation of ion channels. It has also been shown to play a role in the regulation of gene expression, and in the regulation of cellular processes such as cell adhesion and migration.

In addition to its role in intracellular signaling, CHST11 has also been shown to have several potential drug-like properties. For example, it has been shown to be a potential inhibitor of the protein kinase A, which is involved in many cellular processes, including cell growth, differentiation, and survival.

CHST11 has also been shown to interact with several different signaling molecules, including the protein PDGF-尾, which is involved in the regulation of cell growth and differentiation. This suggests that CHST11 may be a potential target for drugs that are designed to interfere with the regulation of these processes.

In conclusion, CHST11 is a protein that has been shown to be involved in a number of different signaling pathways and to have potential drug-like properties. Further research is needed to fully understand its role in these processes and to determine its potential as a drug target.

Protein Name: Carbohydrate Sulfotransferase 11

Functions: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor

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