CILK1: Regulator of Cell Growth, Death and Immune System (G22858)

Target Name: CILK1

NCBI ID: G22858

CILK1: Regulator of Cell Growth, Death and Immune System

CILK1 (ECO) is a protein that is expressed in various tissues throughout the body, including the lungs, heart, kidneys, and intestines. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of CILK1 is its role in cell proliferation and growth. CILK1 promotes the production of new cells by stimulating the growth and division of existing cells. This protein is also involved in the regulation of cell death, and has been shown to play a role in the process of apoptosis, which is a natural and important mechanism for cell turnover and elimination.

In addition to its role in cell growth and differentiation, CILK1 is also involved in the regulation of various signaling pathways that are important for cell function. For example, CILK1 has been shown to be involved in the regulation of theNotch signaling pathway, which is involved in the regulation of cell proliferation and survival.

CILK1 has also been shown to be involved in the regulation of the TGF-β pathway, which is involved in the regulation of cell growth and differentiation. This protein has been shown to play a role in the regulation of the production of various types of tissue-specific genes, and has been implicated in the development of various diseases, including cancer.

In addition to its involvement in cell proliferation and differentiation, CILK1 is also involved in the regulation of cell death and stress. This protein has been shown to play a role in the regulation of cell death, and has been implicated in the development of various diseases, including neurodegenerative disorders.

CILK1 has also been shown to be involved in the regulation of the immune system. This protein has been shown to play a role in the regulation of the production of antibodies, which are important for the immune response.

In conclusion, CILK1 is a protein that is involved in a number of important functions in the body, including cell growth and differentiation, cell death and stress, and immune system regulation. As a result, CILK1 has potential as a drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of CILK1 in these processes, and to develop effective therapies based on this protein.

Protein Name: Ciliogenesis Associated Kinase 1

Functions: Required for ciliogenesis (PubMed:24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity)

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