CHPF: A Protein Regulating GAF-4 and GAF-6 (G79586)

Target Name: CHPF

NCBI ID: G79586

CHPF: A Protein Regulating GAF-4 and GAF-6

CHPF, also known as GLcNACPQ, is a protein that is expressed in various tissues in the body, including the brain, heart, and liver. It is a member of the glycosaminoglycan (GAG) family, which is a type of carbohydrate that is found in many different organisms, including humans. GAGs are involved in a variety of physiological processes in the body, including cell signaling and tissue repair.

One of the functions of CHPF is to regulate the levels of a protein called GLucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II (GAF-4). This protein is involved in the breakdown of a type of carbohydrate called glycosylated proteins, which are modified versions of proteins that contain covalently bound sugars. GAF-4 is the enzyme that transfers the acetyl group from the 4-beta-N-acetylgalactosaminyl group of the protein to the N-acetylgalactosaminyl group. This modification is important for the stability and function of the protein, and is involved in many different cellular processes.

CHPF is also involved in the regulation of the levels of another protein called GLucuronosyl-N-acetylgalactosaminyl-proteoglycan 6-beta-N-acetylgalactosaminyltransferase (GAF-6). This protein is involved in the breakdown of a different type of carbohydrate called N-acetylgalactosaminylated proteins. GAF-6 is the enzyme that transfers the acetyl group from the N-acetylgalactosaminyl group of the protein to the 6-beta-N-acetylgalactosaminyl group.

In addition to its role in regulating the levels of GAF-4 and GAF-6, CHPF is also involved in the regulation of the levels of other proteins, including GLucuronosyl-N-acetylglutamyl-proteoglycan (GLUTP), a protein that is involved in the breakdown of the amino acid glutamate, and GLucuronosyl-N-acetylglutamyl-proteoglycan 6-beta-N-acetylglutamyltransferase (GLUTP-6), a protein that is involved in the breakdown of the amino acid glutamate.

CHPF is also involved in the regulation of the levels of another protein called GLucuronosyl-N-acetyl-glutamyl-proteoglycan (GLUGP). This protein is involved in the breakdown of the amino acid glutamate and is involved in the regulation of many different cellular processes.

As a drug target or biomarker, CHPF is of interest because of its involvement in the regulation of GAF-4 and GAF-6, which are both involved in the regulation of cellular processes that are important for the health and survival of many different organisms. Additionally, CHPF is also involved in the regulation of the levels of other proteins that are involved in a variety of cellular processes, including cell signaling, tissue repair, and inflammation.

Overall, CHPF is a protein that is expressed in various tissues in the body and is involved in the regulation of the levels of a variety of proteins that are involved in many different cellular processes. As a drug target or biomarker, CHPF may be a useful target for the development of new therapies for a variety of diseases.

Protein Name: Chondroitin Polymerizing Factor

Functions: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Seems to act as a specific activating factor for CHSY1 in chondroitin polymerization (PubMed:12716890)

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