PSD: A Protein Involved in Cell Processes and Disease Development
PSD: A Protein Involved in Cell Processes and Disease Development
PSD, or pleckstrin and Sec7 domain containing, is a protein that is expressed in various tissues throughout the body. It is a key regulator of the transport of nucleotides, including DNA and RNA, in and out of cells. The PSD protein has been identified as a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
The PSD protein is composed of several domains, including a nucleotide-binding domain (NBD), a Sec7 domain, and a pleckstrin domain. The NBD is responsible for binding to specific nucleotides, while the Sec7 domain is involved in the formation of the Sec7 complex, which is responsible for transporting nucleotides out of the cell. The pleckstrin domain is responsible for the interaction with the nucleotide carrier protein, which is responsible for transporting the nucleotides into the cell.
PSD has been shown to play a crucial role in the regulation of various cellular processes, including DNA replication, transcription, and translation. It has been shown to interact with numerous proteins, including the transcription factors TFp1 and NF1, and the transport factors NSY and TFII4.
In addition to its role in cellular processes, PSD has also been shown to play a role in the regulation of various diseases. For example, PSD has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. It has also been shown to be involved in the regulation of cancer, including the regulation of cell proliferation and the inhibition of apoptosis.
PSD has also been shown to be a potential biomarker for various diseases, including cancer. The expression of PSD has been shown to be elevated in various types of cancer, including breast cancer, lung cancer, and colorectal cancer. Additionally, PSD has been shown to be associated with the development of cancer-related tissues, such as cancer cells and cancer-associated tissues.
In conclusion, PSD is a protein that has been shown to play a crucial role in a variety of cellular processes and has been implicated in the development and progression of various diseases. As a potential drug target and biomarker, PSD is a promising target for the development of new therapies for a variety of diseases. Further research is needed to fully understand the role of PSD in cellular processes and its potential as a drug target and biomarker.
Protein Name: Pleckstrin And Sec7 Domain Containing
Functions: Guanine nucleotide exchange factor for ARF6 (PubMed:23603394). Induces cytoskeletal remodeling (By similarity)
More Common Targets
PSD2 | PSD3 | PSD4 | PSEN1 | PSEN2 | PSENEN | PSG1 | PSG10P | PSG11 | PSG2 | PSG3 | PSG4 | PSG5 | PSG6 | PSG7 | PSG8 | PSG9 | PSIP1 | PSKH1 | PSKH2 | PSMA1 | PSMA2 | PSMA3 | PSMA3-AS1 | PSMA3P1 | PSMA4 | PSMA5 | PSMA6 | PSMA7 | PSMA8 | PSMB1 | PSMB10 | PSMB11 | PSMB2 | PSMB3 | PSMB3P2 | PSMB4 | PSMB5 | PSMB6 | PSMB7 | PSMB7P1 | PSMB8 | PSMB8-AS1 | PSMB9 | PSMC1 | PSMC1P2 | PSMC1P4 | PSMC1P9 | PSMC2 | PSMC3 | PSMC3IP | PSMC4 | PSMC5 | PSMC6 | PSMD1 | PSMD10 | PSMD10P1 | PSMD11 | PSMD12 | PSMD13 | PSMD14 | PSMD2 | PSMD3 | PSMD4 | PSMD4P1 | PSMD5 | PSMD6 | PSMD6-AS2 | PSMD7 | PSMD8 | PSMD9 | PSME1 | PSME2 | PSME2P2 | PSME2P3 | PSME3 | PSME3IP1 | PSME4 | PSMF1 | PSMG1 | PSMG1-PSMG2 heterodimer | PSMG2 | PSMG3 | PSMG3-AS1 | PSMG4 | PSORS1C1 | PSORS1C2 | PSORS1C3 | PSPC1 | PSPH | PSPHP1 | PSPN | PSRC1 | PSTK | PSTPIP1 | PSTPIP2 | PTAFR | PTAR1 | PTBP1 | PTBP2