Understanding PTPRK: A Potential Drug Target (G5796)

Target Name: PTPRK

NCBI ID: G5796

Other Name(s): protein-tyrosine phosphatase, receptor type, kappa | dJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappa | Protein-tyrosine phosphatase, receptor type, kappa | PTPRK variant 1 | PTPRK variant 3 | Protein-tyrosine phosphatase kappa | Receptor-type tyrosine-protein phosphatase kappa (isoform a) | R-PTP-kappa | Receptor-type tyrosine-protein phosphatase kappa | PTPRK variant 2 | Protein tyrosine phosphatase receptor type K, transcript variant 1 | protein-tyrosine phosphatase kappa | protein tyrosine phosphatase receptor type K | Protein tyrosine phosphatase receptor type K, transcript variant 2 | Receptor-type tyrosine-protein phosphatase kappa (isoform b) | Protein tyrosine phosphatase receptor type K, transcript variant 3 | PTPRK_HUMAN | Receptor-type tyrosine-protein phosphatase kappa (isoform c)

Understanding PTPRK: A Potential Drug Target

Protein-tyrosine phosphatase (PTPRK), also known as protein-tyrosine phosphatase, kappa (PTPK), is a protein that plays a crucial role in cellular signaling. It is an enzyme that is involved in the regulation of many cellular processes, including cell signaling, cell growth, and cell death. PTPRK is a protein that is expressed in many different cell types, including neurons, cardiac cells, and cancer cells. Its role in cellular signaling makes it an attractive drug target for researchers.

PTPRK is a protein that is characterized by its catalytic mechanism. It is an enzyme that catalyzes the transfer of a phosphate group from a phosphate donor to a protein tyrosine residue. This transfer of a phosphate group allows the protein tyrosine to function as a signaling molecule. PTPRK is also known for its role in the regulation of cellular signaling pathways. It is involved in the regulation of many different signaling pathways, including the signaling pathways that are responsible for cell growth, differentiation, and death.

PTPRK is also involved in the regulation of cell signaling pathways that are responsible for the development and progression of cancer. It is has been shown to play a role in the regulation of the angiogenesis, which is the process by which cancer cells develop blood vessels to supply themselves with oxygen and nutrients.

PTPRK is also involved in the regulation of the immune response. It is has been shown to play a role in the regulation of T cell proliferation and differentiation.

PTPRK is a protein that is expressed in many different cell types, including neurons, cardiac cells, and cancer cells. Its role in cellular signaling makes it an attractive drug target for researchers.

In conclusion, PTPRK is a protein that is involved in the regulation of many different cellular processes. Its role in the regulation of cell signaling pathways, including cell growth, differentiation, and death, makes it an attractive drug target for researchers. Further research is needed to fully understand the role of PTPRK in cellular signaling and its potential as a drug target.

Protein Name: Protein Tyrosine Phosphatase Receptor Type K

Functions: Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa

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