TRMT11 Gene as Drug Target for Neurological Disorders (G60487)

Target Name: TRMT11

NCBI ID: G60487

TRMT11 Gene as Drug Target for Neurological Disorders

TRMT11 is a gene that has been identified as a potential drug target or biomarker for the treatment of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

The TRMT11 gene is a non-coding RNA molecule that is located on chromosome 12q34. It is a part of the non-coding RNA molecule class of genetic elements and is involved in the regulation of gene expression.

The TRMT11 gene has been shown to be involved in the development and progression of several neurological disorders. For example, studies have shown that individuals with certain genetic variations in the TRMT11 gene are at increased risk of developing Alzheimer's disease.

One of the most promising aspects of the TRMT11 gene as a drug target is its potential to target a protein called TRMT1, which is a key regulator of microtubules in cells. Microtubules are a network of filaments that help keep cells in a dividing state and are involved in many important cellular processes, including the transport of drugs to the brain.

Research has shown that TRMT1 is a protein that is expressed in the brain and that it is involved in the regulation of microtubule dynamics. It is also known to be a drug target for several other neurological disorders, including Alzheimer's disease and Parkinson's disease.

The TRMT11 gene has also been shown to be involved in the regulation of a protein called Tau, which is also involved in the development and progression of Alzheimer's disease. Tau is a protein that is involved in the formation of microtubules and is also known to be a drug target for several other neurological disorders.

In conclusion, the TRMT11 gene is a promising drug target or biomarker for the treatment of neurological disorders. Further research is needed to fully understand its role in the development and progression of these disorders and to develop effective treatments.

Protein Name: TRNA Methyltransferase 11 Homolog

Functions: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs

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