NABP1: A Non-Coding RNA Molecule with Diverse Roles in Cellular Processes

Target Name: NABP1

NCBI ID: G64859

NABP1: A Non-Coding RNA Molecule with Diverse Roles in Cellular Processes

NABP1 (NABP1 3'UTR overlapping transcript 1) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. NABP1 is a non-coding RNA molecule that has been shown to play a role in regulating gene expression in various cellular contexts.

One of the unique features of NABP1 is its ability to interact with other non-coding RNAs, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs). This interaction between NABP1 and other non-coding RNAs has been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and transcriptional regulation.

In addition to its role in regulating gene expression, NABP1 has also been shown to play a role in the regulation of protein synthesis. NABP1 has been shown to interact with the protein stability and degradation, known as stability-associated protein (SAP) complex. This interaction between NABP1 and SAP has been shown to play a role in the regulation of cellular processes such as protein stability, localization, and degradation.

Another unique feature of NABP1 is its ability to interact with the DNA double helix. NABP1 has been shown to interact with the DNA-binding protein, known as DNA-binding protein 1 (DNBA), which is a component of the NABP1 complex. This interaction between NABP1 and DNA-binding protein 1 has been shown to play a role in the regulation of gene expression and DNA replication.

In addition to its unique interaction with DNA-binding protein 1, NABP1 has also been shown to interact with a variety of other proteins, including the transcription factor, known as transcription factor TFIID. This interaction between NABP1 and TFIID has been shown to play a role in the regulation of gene expression and transcriptional regulation.

Overall, NABP1 is a highly conserved non-coding RNA molecule that has been shown to play a variety of roles in cellular processes. Its unique ability to interact with other non-coding RNAs and proteins makes it an attractive candidate for drug targeting and biomarker development . Further research is needed to fully understand the role of NABP1 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Nucleic Acid Binding Protein 1

Functions: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways

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