Target Name: NAV1
NCBI ID: G89796
Other Name(s): unc53H1 | FLJ14203 | STEERIN1 | KIAA1151 | POMFIL3 | Pore membrane and/or filament interacting like protein 3 | Unc53H1 | Neuron navigator-1 | Neuron navigator 1, transcript variant 1 | KIAA1213 | Neuron navigator 1 | Neuron navigator 1 (isoform 1) | Unc-53 homolog 1 | unc-53 homolog 1 | MGC14961 | Steerin-1 | neuron navigator 1 | NAV1 variant 1 | DKFZp781D0314 | pore membrane and/or filament interacting like protein 3 | NAV1_HUMAN | FLJ12560 | Pore membrane and/or filament-interacting-like protein 3 | UNC53H1

NAV1: A Non-Coding RNA Molecule as A Potential Drug Target and Biomarker for Diseases

NAV1 (unc53H1) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. NAV1 is a key regulator of gene expression in various cell types and is involved in the regulation of cell cycle progression, apoptosis, and cellular signaling pathways.

The NAV1 gene is located on chromosome 16 and has a length of approximately 2,100 nucleotides. It is a non-coding RNA molecule that is expressed in various cell types, including neurons, macrophages, and dendritic cells. NAV1 is known to play a role in the regulation of gene expression and has been shown to regulate the expression of several target genes that are involved in cell cycle progression, apoptosis, and cellular signaling pathways.

One of the most promising aspects of NAV1 is its potential as a drug target. NAV1 has been shown to play a role in the regulation of cell cycle progression and has been linked to the development of several types of cancer, including breast cancer, ovarian cancer , and colorectal cancer. Additionally, NAV1 has been shown to contribute to the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

NAV1 has also been shown to play a role in the regulation of apoptosis, which is the process by which cells undergo programmed cell death. NAV1 has also been shown to regulate the expression of genes that are involved in the regulation of apoptosis, which may have implications for the treatment of neurodegenerative diseases. Additionally, NAV1 has been shown to play a role in the regulation of cellular signaling pathways, including TGF-β signaling, which is a critical pathway involved in the regulation of cell growth and differentiation.

NAV1 has also been shown to play a role in the regulation of stem cell proliferation and differentiation. NAV1 has been shown to regulate the expression of genes that are involved in stem cell proliferation and differentiation, which may have implications for the development of cancer. Additionally , NAV1 has been shown to play a role in the regulation of immune response, which is a critical pathway involved in the regulation of cellular immune responses against infection and disease.

In conclusion, NAV1 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for several diseases. Its role in the regulation of cell cycle progression, apoptosis, and cellular signaling pathways, as well as its potential as a target for cancer and neurodegenerative diseases, makes NAV1 a promising candidate for further investigation. Further studies are needed to fully understand the role of NAV1 in these diseases and to develop effective treatments based on its potential as a drug target.

Protein Name: Neuron Navigator 1

Functions: May be involved in neuronal migration

More Common Targets

NAV2 | NAV2-AS5 | NAV2-AS6 | NAV3 | NAXD | NAXE | nBAF complex | NBAS | NBAT1 | NBDY | NBEA | NBEAL1 | NBEAL2 | NBEAP1 | NBEAP3 | NBL1 | NBN | NBPF1 | NBPF10 | NBPF11 | NBPF12 | NBPF14 | NBPF15 | NBPF17P | NBPF18P | NBPF19 | NBPF20 | NBPF22P | NBPF25P | NBPF26 | NBPF3 | NBPF4 | NBPF5P | NBPF6 | NBPF7P | NBPF8 | NBPF9 | NBR1 | NBR2 | NCALD | NCAM1 | NCAM1-AS1 | NCAM2 | NCAN | NCAPD2 | NCAPD3 | NCAPG | NCAPG2 | NCAPH | NCAPH2 | NCBP1 | NCBP2 | NCBP2-AS1 | NCBP2AS2 | NCBP3 | NCCRP1 | NCDN | NCEH1 | NCF1 | NCF1B | NCF1C | NCF2 | NCF4 | NCF4-AS1 | NCK1 | NCK1-DT | NCK2 | NCKAP1 | NCKAP1L | NCKAP5 | NCKAP5-AS2 | NCKAP5L | NCKIPSD | NCL | NCLN | NCMAP | NCMAP-DT | NCOA1 | NCOA2 | NCOA3 | NCOA4 | NCOA5 | NCOA6 | NCOA7 | NCOR1 | NCOR1P1 | NCOR2 | NCR1 | NCR2 | NCR3 | NCR3LG1 | NCRUPAR | NCS1 | NCSTN | ND1 | ND2 | ND3 | ND4 | ND4L | ND5