NBPF20: A Drug Target / Disease Biomarker (G100288142)

Target Name: NBPF20

NCBI ID: G100288142

Other Name(s): Neuroblastoma breakpoint family member 20 | Neuroblastoma breakpoint family, member 20 | NBPF member 20

NBPF20: A Drug Target / Disease Biomarker

NBPF20 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its full name is neuroblastomatous reticulum-associated protein 20, and it is also known as NBPF20.

NBPF20 is a protein that is characterized by its ability to interact with various molecules, including G protein-coupled receptors (GPCRs), which are a family of transmembrane proteins that play a critical role in cellular signaling. GPCRs are involved in many different processes in the body, including sensory perception, neurotransmitter signaling, and hormone regulation.

One of the unique features of NBPF20 is its ability to form aggregates in response to various signaling molecules. This aggregation of NBPF20 can be either cytoplasmic or secretory, depending on the type of signaling molecule that is used. When NBPF20 is aggregated in response to a GPCR signaling molecule, it can form aggregates that are involved in the regulation of cellular processes such as cell adhesion, migration, and survival.

Another important property of NBPF20 is its ability to interact with the protein tyrosine phosphatase (PTP) enzyme. PTP is an enzyme that is involved in the regulation of many different cellular processes, including cell signaling, DNA replication, and metabolism. NBPF20 has been shown to interact with PTP and to play a role in the regulation of PTP-mediated signaling pathways.

In addition to its ability to interact with PTP, NBPF20 has also been shown to interact with several other proteins, including the transcription factor retinoblastoma gene (RB) and the protein serine/thionylase. These interactions with other proteins are important for the function of NBPF20, as they help to regulate the activity of NBPF20 and to determine its role in various cellular processes.

The potential drug targets for NBPF20 are numerous. For example, NBPF20 has been shown to play a role in the regulation of cell adhesion, which is important for many different cellular processes, including tissue repair and regeneration. Additionally, NBPF20 has been shown to play a role in the regulation of neurotransmitter signaling, which is important for the transmission of signals in the brain.

In addition to its potential drug targets, NBPF20 is also of interest as a biomarker for certain diseases. For example, NBPF20 has been shown to be expressed in the brains of individuals with Alzheimer's disease, a condition that is characterized by the progressive loss of brain cells that are responsible for transmitting signals. Additionally, NBPF20 has been shown to be expressed in the hearts of individuals with heart failure, a condition that is characterized by the progressive loss of heart muscle due to the failure of the heart to pump blood properly.

Overall, NBPF20 is a protein that is of great interest to researchers because of its unique ability to interact with various molecules, including GPCRs and PTPs. Its potential drug targets and biomarker status make NBPF20 an attractive target for future research.

Protein Name: NBPF Member 20

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