NCSTN: A Promising Gene Expression Biomarker (G23385)
NCSTN: A Promising Gene Expression Biomarker
NCSTN (Nucleotide-Coded STNs) are a type of gene expression biomarker that encodes the genetic information within the non-coding regions of genes. These biomarkers can be used to identify potential drug targets, biomarkers for diagnostic purposes, or for understanding the underlying biology of a disease.
NCSTN is a gene expression biomarker that is expressed in various tissues and cell types, including brain, heart, and muscle. It is composed of a unique array of non-coding RNA molecules, which are encoded by the nucleotide-coded STNs. These RNA molecules are highly stable and can be used for a variety of applications, including drug discovery and diagnosis.
One of the key advantages of NCSTN is its ability to be used as a drug target. The non-coding RNA molecules that make up NCSTN have been shown to play important roles in a variety of physiological processes, including cell signaling, gene regulation, and cellular signaling pathways. As a result, many researchers and pharmaceutical companies are interested in using NCSTN as a drug target for a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease.
In addition to its potential as a drug target, NCSTN also has the potential as a biomarker for a variety of diseases. For example, some studies have shown that NCSTN levels can be affected by a variety of factors, including systemic stress, infection, and certain medications. As a result, NCSTN has the potential to serve as a biomarker for a variety of diseases, including heart disease, cancer, and neurodegenerative diseases.
Another promising application of NCSTN is its potential as a tool for understanding the underlying biology of a disease. The non-coding RNA molecules that make up NCSTN have been shown to play important roles in the regulation of a wide variety of cellular processes, including cell signaling, gene expression, and cellular signaling pathways. As a result, NCSTN can be used to gain insights into the underlying biology of a disease and to identify potential new targets for therapy.
Overall, NCSTN is a promising gene expression biomarker that has the potential to be used as a drug target, a biomarker for diagnostic purposes, or for understanding the underlying biology of a disease. Further research is needed to fully understand the potential of NCSTN and its applications in these areas.
Protein Name: Nicastrin
Functions: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546, PubMed:30630874). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels
More Common Targets
ND1 | ND2 | ND3 | ND4 | ND4L | ND5 | ND6 | NDC1 | NDC80 | NDC80 kinetochore complex | NDE1 | NDEL1 | NDFIP1 | NDFIP2 | NDN | NDNF | NDOR1 | NDP | NDRG1 | NDRG2 | NDRG3 | NDRG4 | NDST1 | NDST1-AS1 | NDST2 | NDST3 | NDST4 | NDUFA1 | NDUFA10 | NDUFA11 | NDUFA12 | NDUFA13 | NDUFA2 | NDUFA3 | NDUFA3P3 | NDUFA4 | NDUFA4L2 | NDUFA5 | NDUFA5P11 | NDUFA6 | NDUFA6-DT | NDUFA7 | NDUFA8 | NDUFA9 | NDUFAB1 | NDUFAF1 | NDUFAF2 | NDUFAF3 | NDUFAF4 | NDUFAF4P1 | NDUFAF5 | NDUFAF6 | NDUFAF7 | NDUFAF8 | NDUFB1 | NDUFB10 | NDUFB11 | NDUFB2 | NDUFB2-AS1 | NDUFB3 | NDUFB4 | NDUFB5 | NDUFB6 | NDUFB7 | NDUFB8 | NDUFB9 | NDUFC1 | NDUFC2 | NDUFC2-KCTD14 | NDUFS1 | NDUFS2 | NDUFS3 | NDUFS4 | NDUFS5 | NDUFS6 | NDUFS7 | NDUFS8 | NDUFV1 | NDUFV2 | NDUFV2P1 | NDUFV3 | NEAT1 | NEB | NEBL | NECAB1 | NECAB2 | NECAB3 | NECAP1 | NECAP2 | NECTIN1 | NECTIN2 | NECTIN3 | NECTIN3-AS1 | NECTIN4 | NEDD1 | NEDD4 | NEDD4L | NEDD8 | NEDD8-activating enzyme E1 | NEDD8-MDP1