NDUFS1: Key Enzyme in The NADH-coenzyme Q (NADH) Cycle (G4719)
NDUFS1: Key Enzyme in The NADH-coenzyme Q (NADH) Cycle
National Developmental Umbrella for Services (NDUFS1), also known as NADH-coenzyme Q (NADH) reductase, is a enzyme that plays a crucial role in the production of energy in the cells of all living organisms. It is a key enzyme in the citric acid cycle, also known as the Krebs cycle or TCA cycle, which is responsible for generating the energy-carrying molecule ATP fromADenosine (A) and Pyruvate (P).
NDUFS1 is a 22-kDa protein that is expressed in most organisms, including bacteria, archaea, and eukaryotes. It is a subunit of the E1 enzyme complex of the citric acid cycle and is located in the cytoplasm of the cell.
The NADH-coenzyme Q (NADH) cycle is a critical metabolic pathway that generates the majority of the energy for the cell. It is a linear reaction that involves the transfer of electrons from NAD+ (nicotinamide adenine dinucleotide) to FAD (flavin adenine dinucleotide) to produce NADH, which is then used to produce ATP through the process of oxidative phosphorylation.
NDUFS1 is a key enzyme in the NADH-coenzyme Q (NADH) cycle by participating in the transfer of electrons from NAD+ to FAD to produce NADH. The NADH cycle is the first step in the citric acid cycle and is critical for the production of ATP, which is the energy-carrying molecule of the cell.
NDUFS1 is a protein that is expressed in most organisms and is involved in the production of energy through the NADH-coenzyme Q (NADH) cycle. It is a subunit of the E1 enzyme complex of the NADH-coenzyme Q (NADH) cycle and is located in the cytoplasm of the cell.
The NADH-coenzyme Q (NADH) cycle is a critical metabolic pathway that generates the majority of the energy for the cell. It is a linear reaction that involves the transfer of electrons from NAD+ to FAD to produce NADH, which is then used to produce ATP through the process of oxidative phosphorylation.
NDUFS1 is a key enzyme in the NADH-coenzyme Q (NADH) cycle by participating in the transfer of electrons from NAD+ to FAD to produce NADH. The NADH cycle is the first step in the citric acid cycle and is critical for the production of ATP, which is the energy-carrying molecule of the cell.
NDUFS1 is a protein that is expressed in most organisms and plays a crucial role in the production of energy through the NADH-coenzyme Q (NADH) cycle. It is a subunit of the E1 enzyme complex of the NADH-coenzyme Q (NADH) cycle and is located in the cytoplasm of the cell.
The NADH-coenzyme Q (NADH) cycle is a critical metabolic pathway that generates the majority of the energy for the cell. It is a linear reaction that involves the transfer of electrons from NAD+ to FAD to produce NADH, which is then used to produce ATP through the process of oxidative phosphorylation.
NDUFS1 is a key enzyme in the NADH-coenzyme Q (NADH) cycle by participating in the transfer of electrons from NAD+ to FAD to produce NADH. The NADH cycle is the first step in the citric acid cycle and is critical for the production of ATP, which is the energy-carrying molecule of the cell.
In conclusion, NDUFS1 is a protein that is involved in
Protein Name: NADH:ubiquinone Oxidoreductase Core Subunit S1
Functions: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:31557978). Essential for catalysing the entry and efficient transfer of electrons within complex I (PubMed:31557978). Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903, PubMed:31557978)
More Common Targets
NDUFS2 | NDUFS3 | NDUFS4 | NDUFS5 | NDUFS6 | NDUFS7 | NDUFS8 | NDUFV1 | NDUFV2 | NDUFV2P1 | NDUFV3 | NEAT1 | NEB | NEBL | NECAB1 | NECAB2 | NECAB3 | NECAP1 | NECAP2 | NECTIN1 | NECTIN2 | NECTIN3 | NECTIN3-AS1 | NECTIN4 | NEDD1 | NEDD4 | NEDD4L | NEDD8 | NEDD8-activating enzyme E1 | NEDD8-MDP1 | NEDD9 | NEFH | NEFHP1 | NEFL | NEFM | NEGR1 | NEGR1-IT1 | NEIL1 | NEIL2 | NEIL3 | NEK1 | NEK10 | NEK11 | NEK2 | NEK2-DT | NEK3 | NEK4 | NEK5 | NEK6 | NEK7 | NEK8 | NEK9 | NELF Complex | NELFA | NELFB | NELFCD | NELFE | NELL1 | NELL2 | NEMF | NEMP1 | NEMP2 | NEMP2-DT | NENF | NEO1 | NEPRO | NES | NET1 | NETO1 | NETO1-DT | NETO2 | Netrin receptor | NEU1 | NEU2 | NEU3 | NEU4 | NEURL1 | NEURL1-AS1 | NEURL1B | NEURL2 | NEURL3 | NEURL4 | NEUROD1 | NEUROD2 | NEUROD4 | NEUROD6 | NEUROG1 | NEUROG2 | NEUROG3 | Neuromedin U Receptor | Neuronal acetylcholine receptor alpha2beta2 receptor | Neuronal Acetylcholine Receptor alpha3alpha5beta2 Receptor | Neuropeptide FF Receptor | Neuropeptide Y receptor (NPY-R) | Neurotensin receptor | Neurotrophic Factor | Neurotrophic Tyrosine Kinase Receptor (TRK) | NEXMIF | NEXN | NEXN-AS1