NF-L: A Key Regulator of The Neurofilament System (G4747)

Target Name: NEFL

NCBI ID: G4747

NF-L: A Key Regulator of The Neurofilament System

Neurofilament subunit (NF-L) is a protein that plays a crucial role in the structure and function of neural filaments, which are the protein building blocks that give shape to the myelin sheath surrounding the neural fibers. NF-L is a subunit of the neurofilament protein family and is composed of four distinct subunits that are held together by non-covalent interactions.

The neurofilament system is composed of two main types of proteins: the protein subunits and the non-protein subunits. The protein subunits are responsible for the structural integrity of the neurofilament system, while the non-protein subunits are involved in the regulation of the neurofilament system.

NF-L is a non-protein subunit that is composed of four subunits: alpha, beta, gamma, and delta. These subunits are held together by non-covalent interactions, which include disulfide bonds and hydrogen bonding. The non-covalent interactions between the subunits are important for the stability of the neurofilament system and for the regulation of the NF-L structure and function.

One of the key functions of NF-L is its role in the regulation of the neurofilament system. NF-L plays a critical role in the stability of the microtubules, which are the structural units that give shape to the myelin sheath surrounding the neural fibers. The microtubules are composed of the protein subunit alpha-tubulin and the non-protein subunit p180.

NF-L is also involved in the regulation of the neurofilament system in terms of its stability. NF-L has been shown to play a critical role in the regulation of microtubule stability and dynamics. This is important for the proper functioning of the neural system, as the stability of the microtubules is directly related to the stability and function of the neural fibers.

Another important function of NF-L is its role in the regulation of the neurofilament system in terms of its dynamics. NF-L plays a critical role in the regulation of the dynamics of the microtubules, which is important for the proper functioning of the neural system.

In conclusion, NF-L is a non-protein subunit that is composed of four distinct subunits that are held together by non-covalent interactions. The non-covalent interactions between the subunits play a critical role in the stability and function of the neurofilament system, which is important for the proper functioning of the neural system. As a result, NF-L is a potential drug target and may be useful as a biomarker for the diagnosis and treatment of neurodegenerative diseases.

Protein Name: Neurofilament Light Chain

Functions: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity)

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