NCAM1-AS1: A Potential Drug Target and Biomarker (G100288346)

Target Name: NCAM1-AS1

NCBI ID: G100288346

Other Name(s): NCAM1 antisense RNA1

NCAM1-AS1: A Potential Drug Target and Biomarker

Non-coding RNA (ncRNA) molecules have been identified as key regulators in various diseases, including cancer. One such ncRNA, named NCAM1-AS1, has been shown to play a significant role in the development and progression of colorectal cancer (CRC). This RNA has also been identified as a potential drug target and biomarker for the treatment of CRC.

The NCAM1 gene is located on chromosome 6 and encodes for a protein known as NCAM1. NCAM1 is a cell adhesion molecule that is expressed in various tissues and organs, including the gut epithelial tissue, where it is involved in cell-cell adhesion and tissue architecture. In addition to its role in cell adhesion, NCAM1 has also been shown to play a role in various signaling pathways, including the TGF-β pathway.

The TGF-β pathway is a well-established signaling pathway that is involved in the regulation of cell growth, differentiation, and survival. The TGF-β pathway is activated by various factors, including transforming growth factor-beta (TGF-β), which is a potent cytokine that promotes cell proliferation and survival.

NCAM1 has been shown to be involved in the TGF-β pathway by regulating the activity of the transcription factor, transforminger-1 (T-1). T-1 is a critical transcription factor that is involved in the regulation of various cellular processes, including cell growth, differentiation, and apoptosis. NCAM1 has been shown to physically interact with T-1 and regulate its activity, which may have implications for the regulation of cellular processes that are relevant to cancer development and progression.

In addition to its role in the TGF-β pathway, NCAM1 has also been shown to play a role in the regulation of cell-cell adhesion. NCAM1 has been shown to interact with the protein E-cadherin, which is a cell adhesion molecule that is involved in the regulation of cell-cell adhesion and tissue architecture. The interaction between NCAM1 and E-cadherin has been shown to play a role in the regulation of cellular processes that are relevant to cancer development and progression, including the regulation of tumor cell migration and the maintenance of cancer stem cell self-renewal.

The potential drug target for NCAM1 is the regulation of cell-cell adhesion and the regulation of various cellular processes that are relevant to cancer development and progression. Drugs that are able to modulate the activity of NCAM1 may have potential as anti-cancer agents.

NCAM1 has also been shown to be involved in the regulation of apoptosis, which is a process that is involved in the regulation of cell death. Apoptosis is a natural process that is involved in the regulation of cellular processes, including cell growth, differentiation, and homeostasis. NCAM1 has been shown to be involved in the regulation of apoptosis by regulating the activity of the protein Bcl-2, which is a protein that is involved in the regulation of apoptosis.

The potential biomarker for NCAM1-AS1 is the regulation of cell-cell adhesion and the regulation of apoptosis. These processes are relevant to the development and progression of cancer, and may be potential targets for anti-cancer agents. The regulation of cell-cell adhesion by NCAM1 may be relevant to the regulation of tumor cell migration, and the regulation of apoptosis by NCAM1 may be relevant to the regulation of cancer stem cell self-renewal. Further research is needed to determine the full role of NCAM1 in the regulation of cell-cell adhesion and apoptosis, and to identify potential drug targets for these processes.

In conclusion, NCAM1-AS1 is a ncRNA that is involved in the regulation of various cellular processes that are relevant to cancer development and progression. The regulation of cell-cell adhesion and apoptosis by NCAM1 may be potential targets for anti-cancer agents. Further research is needed to fully understand the role of NCAM1 in these processes and to identify potential drug targets.

Protein Name: NCAM1 Antisense RNA1

More Common Targets