NCAPH: A Potential Cancer Drug Target (G23397)
NCAPH: A Potential Cancer Drug Target
NCAPH (Barren Homolog 1) is a protein that is expressed in the placenta, and has been shown to play a role in the development and maintenance of cancer. It is also a potential drug target for the treatment of various diseases, including cancer.
NCAPH is a member of the TGF-β pathway, a well-established pathway that plays a role in the development and maintenance of cancer. The TGF-β pathway is a complex signaling pathway that is involved in the regulation of cell growth, differentiation, and survival. NCAPH is a key regulator in this pathway, and is involved in the development of cancer stem cells.
Studies have shown that NCAPH plays a role in the development of various types of cancer, including breast, ovarian, and prostate cancer. In addition, NCAPH has also been shown to be involved in the regulation of cell growth and differentiation, and is involved in the development of various types of cancer stem cells.
NCAPH is also a potential drug target for the treatment of various diseases, including cancer. By inhibiting the activity of NCAPH, researchers have shown that they can inhibit the growth and development of cancer stem cells, and can potentially lead to the treatment of cancer.
In addition to its potential as a drug target, NCAPH is also a valuable biomarker for the diagnosis and treatment of cancer. The TGF-β pathway is a well-established pathway that is involved in the development and maintenance of cancer, and the activity of NCAPH can be used as a biomarker for the diagnosis and treatment of cancer.
Overall, NCAPH is a protein that is involved in the development and maintenance of cancer, and has been shown to be a potential drug target for the treatment of various diseases, including cancer. Further research is needed to fully understand its role in the development and maintenance of cancer, as well as its potential as a drug target.
Protein Name: Non-SMC Condensin I Complex Subunit H
Functions: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (PubMed:11136719). Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959)
More Common Targets
NCAPH2 | NCBP1 | NCBP2 | NCBP2-AS1 | NCBP2AS2 | NCBP3 | NCCRP1 | NCDN | NCEH1 | NCF1 | NCF1B | NCF1C | NCF2 | NCF4 | NCF4-AS1 | NCK1 | NCK1-DT | NCK2 | NCKAP1 | NCKAP1L | NCKAP5 | NCKAP5-AS2 | NCKAP5L | NCKIPSD | NCL | NCLN | NCMAP | NCMAP-DT | NCOA1 | NCOA2 | NCOA3 | NCOA4 | NCOA5 | NCOA6 | NCOA7 | NCOR1 | NCOR1P1 | NCOR2 | NCR1 | NCR2 | NCR3 | NCR3LG1 | NCRUPAR | NCS1 | NCSTN | ND1 | ND2 | ND3 | ND4 | ND4L | ND5 | ND6 | NDC1 | NDC80 | NDC80 kinetochore complex | NDE1 | NDEL1 | NDFIP1 | NDFIP2 | NDN | NDNF | NDOR1 | NDP | NDRG1 | NDRG2 | NDRG3 | NDRG4 | NDST1 | NDST1-AS1 | NDST2 | NDST3 | NDST4 | NDUFA1 | NDUFA10 | NDUFA11 | NDUFA12 | NDUFA13 | NDUFA2 | NDUFA3 | NDUFA3P3 | NDUFA4 | NDUFA4L2 | NDUFA5 | NDUFA5P11 | NDUFA6 | NDUFA6-DT | NDUFA7 | NDUFA8 | NDUFA9 | NDUFAB1 | NDUFAF1 | NDUFAF2 | NDUFAF3 | NDUFAF4 | NDUFAF4P1 | NDUFAF5 | NDUFAF6 | NDUFAF7 | NDUFAF8 | NDUFB1