INTS15: Key Component of Integrin System (G79034)

Target Name: INTS15

NCBI ID: G79034

INTS15: Key Component of Integrin System

INTS15, also known as Integrator complex subunit 15, is a protein that is expressed in many different tissues and organs in the human body. It is a key component of the integrin system, which is a complex protein that plays a vital role in cell-cell and cell-extracellular matrix interactions.

The integrin system helps cells stick together, move around, and respond to stimuli in a coordinated manner. INTS15 is one of the proteins that is part of this system. It is made up of four subunits that are held together by non-covalent bonds. These subunits give INTS15 its unique structure and function.

One of the key functions of INTS15 is its role in cell-cell adhesion. Adhesion is the process by which cells stick together and form tissues. INTS15 helps cells stick together by interacting with the protein ICN (intercellular junction molecule). ICN is also a key component of the integrin system, and it helps cells stick together by interacting with INTS15.

Another function of INTS15 is its role in cell migration. Migration is the process by which cells move from one location to another in the body. INTS15 helps cells migrate by interacting with the protein FAK (focal adhesion kinase). FAK is another key component of the integrin system, and it helps cells stick together by interacting with INTS15.

INTS15 is also involved in many other processes in the body. For example, it is involved in the development and maintenance of tissues, such as skin and heart tissue. It is also involved in the regulation of cell growth and the development of cancer.

As a drug target, INTS15 is a promising target for the treatment of many different diseases. For example, it is being targeted as a potential treatment for cancer, including breast, ovarian, and prostate cancers. INTS15 is also being targeted as a potential treatment for skin diseases, such as acne and psoriasis.

In addition to its potential as a drug target, INTS15 is also a valuable biomarker. Its unique structure and function make it an ideal candidate for use as a diagnostic marker. For example, INTS15 has been used to diagnose a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Overall, INTS15 is a protein that plays a vital role in the integrin system and many other processes in the body. Its unique structure and function make it an ideal candidate for use as a drug target and a biomarker. Further research is needed to fully understand its role in the body and its potential as a therapeutic agent.

Protein Name: Integrator Complex Subunit 15

Functions: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing

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