Target Name: RBFA
NCBI ID: G79863
Other Name(s): ribosome binding factor A | Ribosome binding factor A, transcript variant 1 | RBFA_HUMAN | ribosome binding factor A (putative) | C18orf22 | RBFA variant 1 | Putative ribosome-binding factor A, mitochondrial (isoform 1) | Hypothetical protein LOC79863 | FLJ21172 | HsT169 | Putative ribosome-binding factor A, mitochondrial

RBFA: A Protein with A Wide Range of Functions in Eukaryotic Cells

Ribosome binding factor A (RBFA) is a protein that plays a critical role in the regulation of gene expression in eukaryotic cells. It is a member of the RNA binding proteins family and is involved in the binding of RNA to the ribosome. RBFA has been identified as a potential drug target and a biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

RBFA is a 21-kDa protein that is expressed in most tissues of the body. It is highly conserved, with a calculated pI of 11.95 nM and a calculated hydrophobicity index of 154.8. RBFA is predominantly localized to the cytoplasm and is present in high levels in the brain, heart, and liver. It is also expressed in the blood and lymph fluid.

RBFA is involved in the regulation of gene expression by binding to specific RNA binding site on target RNAs. It has been shown to interact with a wide range of molecules, including RNA-protein interactions, DNA-protein interactions, and protein-protein interactions.

One of the most well-studied functions of RBFA is its role in cell signaling pathways. RBFA has been shown to be involved in the regulation of cell cycle progression, apoptosis, angiogenesis, and inflammation.

RBFA has also been shown to play a role in cancer progression. It has been shown to be involved in the regulation of cancer cell growth, invasion, and metastasis. Additionally, RBFA has also been shown to be involved in the regulation of cellular processes that are important for the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its role in cellular signaling pathways, RBFA has also been shown to be involved in the regulation of protein translation. It has been shown to play a role in the regulation of protein synthesis by binding to specific protein coding regions of mRNAs.

RBFA has also been shown to be involved in the regulation of cellular immune response. It has been shown to play a role in the regulation of T cell development and function, and has also been shown to be involved in the regulation of immune cell inflammation.

RBFA has also been shown to be involved in the regulation of cell adhesion. It has been shown to play a role in the regulation of tight junction formation in epithelial cells, which is important for the regulation of cell-cell communication and the development of cancer.

In conclusion, RBFA is a protein that has a wide range of functions in cellular signaling pathways, including cell cycle progression, apoptosis, angiogenesis, and inflammation. It has also been shown to play a role in the regulation of protein translation, cellular immune response , and cell adhesion. As a result, RBFA has potential as a drug target and a biomarker for a wide range of diseases.

Protein Name: Ribosome Binding Factor A

More Common Targets

RBFOX1 | RBFOX2 | RBFOX3 | RBIS | RBKS | RBL1 | RBL2 | RBM10 | RBM11 | RBM12 | RBM12B | RBM14 | RBM14-RBM4 | RBM15 | RBM15-AS1 | RBM15B | RBM17 | RBM17P1 | RBM18 | RBM19 | RBM20 | RBM22 | RBM22P1 | RBM23 | RBM24 | RBM25 | RBM26 | RBM26-AS1 | RBM27 | RBM28 | RBM3 | RBM33 | RBM34 | RBM38 | RBM39 | RBM4 | RBM41 | RBM42 | RBM43 | RBM43P1 | RBM44 | RBM45 | RBM46 | RBM47 | RBM48 | RBM48P1 | RBM4B | RBM5 | RBM5-AS1 | RBM6 | RBM7 | RBM8A | RBMS1 | RBMS1P1 | RBMS2 | RBMS2P1 | RBMS3 | RBMS3-AS3 | RBMX | RBMX2 | RBMX2P1 | RBMXL1 | RBMXL2 | RBMXL3 | RBMY1A1 | RBMY1B | RBMY1D | RBMY1F | RBMY1J | RBMY2EP | RBMY2FP | RBP1 | RBP2 | RBP3 | RBP4 | RBP5 | RBP7 | RBPJ | RBPJL | RBPJP2 | RBPMS | RBPMS-AS1 | RBPMS2 | RBSN | RBX1 | RC3H1 | RC3H2 | RCAN1 | RCAN2 | RCAN3 | RCAN3AS | RCBTB1 | RCBTB2 | RCC1 | RCC1L | RCC2 | RCCD1 | RCE1 | RCHY1 | RCL1