Target Name: RBFOX3
NCBI ID: G146713
Other Name(s): uncharacterized LOC102723900 | RNA binding protein fox-1 homolog 3 | RNA-binding protein fox-1 homolog 3 | Fox-1 homolog C | Neuronal nuclei antigen | RNA binding protein fox-1 homolog 3 (isoform 1) | RFOX3_HUMAN | hexaribonucleotide binding protein 3 | fox-1 homolog C | RNA binding protein, fox-1 homolog 3 | FLJ56884 | hypothetical protein LOC644767 | neuN antigen | RNA binding fox-1 homolog 3, transcript variant 1 | HRNBP3 | Neuronal nuclei | FLJ58356 | NEUN | NeuN antigen | FLJ44838 | RNA binding fox-1 homolog 3 | neuronal nuclei antigen | OTTHUMP00000196558 | FOX-3 | Hexaribonucleotide binding protein 3 | RBFOX3 variant 1 | FOX3

RBFOX3: A Potential Drug Target and Biomarker

Ribofoxin (RBFOX3) is a protein that is expressed in various tissues of the body, including the brain. It is a small molecule that has been shown to have a variety of functions, including modulating the activity of genes, cell signaling, and neurotransmitter release . Despite its importance, RBFOX3 is not well understood, and its potential uses are limited. However, recent studies have suggested that RBFOX3 may be a drug target and biomarker.

The Importance of RBFOX3

Ribofoxin is a protein that plays a critical role in the regulation of gene expression and cell signaling. It is a DNA methyltransferase that helps to keep gene promoters silent, and it also helps to remove methyl groups from the promoter region, allowing for active gene expression . RBFOX3 is also involved in the regulation of microRNA (miRNA) levels, which are small non-coding RNAs that play a variety of roles in gene expression.

In addition to its role in gene regulation, RBFOX3 is also involved in the regulation of cellular signaling. It has been shown to play a role in the regulation of neural plasticity, which is the ability of the brain to change and adapt over time. RBFOX3 has also been shown to be involved in the regulation of neurotransmitter release, which is the release of chemical messengers from neurons that help to communicate with other neurons and cells.

The Potential Role of RBFOX3 as a Drug Target

Despite its importance, RBFOX3 is not well understood, and its potential uses are limited. However, recent studies have suggested that RBFOX3 may be a drug target. One potential mechanism by which RBFOX3 could be targeted is through its role in the regulation of gene expression . Drugs that target RBFOX3 with specificity for its active site could potentially inhibit its ability to regulate gene expression and have therapeutic benefits.

Another potential mechanism by which RBFOX3 could be targeted is through its role in the regulation of cellular signaling. Drugs that target RBFOX3 with specificity for its active site could potentially inhibit its ability to regulate cellular signaling and have therapeutic benefits.

The Potential Role of RBFOX3 as a Biomarker

In addition to its potential uses as a drug target, RBFOX3 may also be a valuable biomarker. Its role in the regulation of gene expression and cellular signaling makes it a potential candidate for use as a biomarker for a variety of neurological and psychiatric disorders. For For example, drugs that target RBFOX3 with specificity for its active site may be effective in treating neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease.

Conclusion

Ribofoxin (RBFOX3) is a protein that is expressed in various tissues of the body, including the brain. It is a small molecule that has been shown to have a variety of functions, including modulating the activity of genes, cell signaling, and neurotransmitter release . Despite its importance, RBFOX3 is not well understood, and its potential uses are limited. However, recent studies have suggested that RBFOX3 may be a drug target and biomarker. Its potential use as a drug target and biomarker makes it an attractive target for future research.

Protein Name: RNA Binding Fox-1 Homolog 3

Functions: Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD)

More Common Targets

RBIS | RBKS | RBL1 | RBL2 | RBM10 | RBM11 | RBM12 | RBM12B | RBM14 | RBM14-RBM4 | RBM15 | RBM15-AS1 | RBM15B | RBM17 | RBM17P1 | RBM18 | RBM19 | RBM20 | RBM22 | RBM22P1 | RBM23 | RBM24 | RBM25 | RBM26 | RBM26-AS1 | RBM27 | RBM28 | RBM3 | RBM33 | RBM34 | RBM38 | RBM39 | RBM4 | RBM41 | RBM42 | RBM43 | RBM43P1 | RBM44 | RBM45 | RBM46 | RBM47 | RBM48 | RBM48P1 | RBM4B | RBM5 | RBM5-AS1 | RBM6 | RBM7 | RBM8A | RBMS1 | RBMS1P1 | RBMS2 | RBMS2P1 | RBMS3 | RBMS3-AS3 | RBMX | RBMX2 | RBMX2P1 | RBMXL1 | RBMXL2 | RBMXL3 | RBMY1A1 | RBMY1B | RBMY1D | RBMY1F | RBMY1J | RBMY2EP | RBMY2FP | RBP1 | RBP2 | RBP3 | RBP4 | RBP5 | RBP7 | RBPJ | RBPJL | RBPJP2 | RBPMS | RBPMS-AS1 | RBPMS2 | RBSN | RBX1 | RC3H1 | RC3H2 | RCAN1 | RCAN2 | RCAN3 | RCAN3AS | RCBTB1 | RCBTB2 | RCC1 | RCC1L | RCC2 | RCCD1 | RCE1 | RCHY1 | RCL1 | RCN1 | RCN1P2 | RCN2