Study on RBM45: Regulation of MiRNA and Gene Expression (G129831)

Target Name: RBM45

NCBI ID: G129831

Study on RBM45: Regulation of MiRNA and Gene Expression

RNA binding motif (RBM) proteins play a crucial role in regulating gene expression and are involved in various cellular processes. RBM45, a protein encoded by the CDN1 gene, is one of the RBM proteins that has been well-studied. The RBM45 protein is a key regulator of microRNA (miRNA) levels, which are small non-coding RNAs that play a pivotal role in post-transcriptional gene regulation. RBM45 is also known as transcript variant 1 (TV1) protein.

RBM45 is a 21-kDa protein that is composed of 155 amino acid residues. It has a characteristic RBM domain that is commonly found in RBM proteins. The RBM domain is responsible for the protein's ability to bind to specific RNA molecules. RBM45 has four known RNA binding motifs (RBMs) that are involved in the regulation of gene expression.

The first RBM is a 10 amino acid motif located at its N-terminus. This motif is involved in the regulation of miRNA stability and target selection. RBM45 contains a conserved Ser-Pro-Asp (SPA) sequence that is known to play a critical role in the formation of RNA-protein complexes. This motif is also present in several other RBM proteins, including RBM1, RBM2, and RBM5.

The second RBM is a 20 amino acid motif located at its C-terminus. This motif is involved in the regulation of miRNA stability and target selection. RBM45 contains a conserved Asp-Ty-Asn (ATASN) sequence that is known to play a critical role in the formation of RNA-protein complexes. This motif is also present in several other RBM proteins, including RBM1, RBM2, RBM5, and RSM1.

The third RBM is a 25 amino acid motif located at its N-terminus. This motif is involved in the regulation of miRNA stability and target selection. RBM45 contains a conserved Asp-Ty-Asn (ATASN) sequence that is known to play a critical role in the formation of RNA-protein complexes. This motif is also present in several other RBM proteins, including RBM1, RBM2, RBM5, and RSM1.

The fourth RBM is a 30 amino acid motif located at its C-terminus. This motif is involved in the regulation of miRNA stability and target selection. RBM45 contains a conserved Asp-Ty-Asn (ATASN) sequence that is known to play a critical role in the formation of RNA-protein complexes. This motif is also present in several other RBM proteins, including RBM1, RBM2, RBM5, and RSM1.

RBM45 has been shown to play a critical role in the regulation of miRNA levels. miRNA are small non-coding RNAs that are involved in post-transcriptional gene regulation. They are produced by RNA polymerase II and can interact with various protein factors to regulate gene expression. RBM45 has been shown to interact with miRNA-21, a well-known regulator of cell growth and differentiation.

RBM45 has also been shown to play a critical role in the regulation of gene expression. It has been shown to interact with various protein factors, including the transcription factors, to regulate their activity. This interaction between RBM45 and transcription factors is critical for the regulation of gene expression.

In addition to its role in the regulation of miRNA and gene expression, RBM45 has also been shown to play a critical role in the regulation of cell survival. It has been shown to interact with various cellular stress

Protein Name: RNA Binding Motif Protein 45

Functions: RNA-binding protein with binding specificity for poly(C). May play an important role in neural development

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