Target Name: RCN2
NCBI ID: G5955
Other Name(s): calcium-binding protein ERC-55 | reticulocalbin 2 | reticulocalbin 2, EF-hand calcium binding domain (endoplasmic reticulum calcium-binding protein, 55kD) | ERC-55 | RCN2_HUMAN | RCN2 variant 1 | Reticulocalbin 2, transcript variant 1 | Reticulocalbin-2 (isoform a) | TCBP49 | E6BP | Reticulocalbin-2 | ERC55 | Calcium-binding protein ERC-55 | Reticulocalbin 2, EF-hand calcium binding domain (endoplasmic reticulum calcium-binding protein, 55kD) | E6-binding protein

RCN2: A Calcium-Binding Protein as a Drug Target and Biomarker

Calcium-binding proteins are a diverse family of molecules that play a crucial role in various cellular processes, including intracellular signaling, muscle contractions, and nerve function. One of the most well-known calcium-binding proteins is RCN2 (regeneration-associated protein 2), which is expressed in various tissues and is involved in several cellular processes. In this article, we will discuss RCN2 as a drug target and biomarker.

Drug Target

RCN2 is a protein that is expressed in various tissues, including muscle, nerve, and heart. It is involved in several cellular processes, including intracellular signaling, cytoskeletal organization, and neurotransmission. One of the most significant functions of RCN2 is its role in intracellular signaling. RCN2 is involved in the regulation of intracellular signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and progression of many diseases, including cancer.

In addition to its role in intracellular signaling, RCN2 is also involved in the regulation of extracellular signaling. It is involved in the regulation of calcium homeostasis, which is essential for many cellular processes, including muscle contractions, nerve function, and platelet function. The regulation of calcium homeostasis is critical for maintaining the integrity of many cellular processes and is a key factor in the development and progression of many diseases, including hypertension, diabetes, and heart disease.

Biomarker

RCN2 is also a potential biomarker for several diseases, including cancer. Its involvement in intracellular signaling and calcium homeostasis makes it an attractive target for the development of new diagnostic tools and therapeutic approaches for cancer. One of the most promising strategies for the development of RCN2-based biomarkers is the use of gene editing techniques to create RNA-containing constructs that can be used for diagnostic assays. These constructs can be used to detect RCN2 expression in various tissues and cells, providing a sensitive and reliable method for the diagnosis of cancer.

In addition to its potential as a biomarker, RCN2 is also a drug target for several diseases. Its involvement in intracellular signaling and calcium homeostasis makes it an attractive target for small molecules that can modulate its function. One of the most promising strategies for the development of RCN2-based drugs is the use of high-throughput screening techniques to identify small molecules that can modulate RCN2 function. These drugs can then be tested for their efficacy in a variety of diseases, including cancer.

Conclusion

In conclusion, RCN2 is a protein that is involved in several cellular processes and is a potential drug target for the development of new therapies for cancer. Its role in intracellular signaling and calcium homeostasis makes it an attractive target for small molecules that can modulate its function. As a potential biomarker, RCN2 can be used to diagnose and monitor the progression of cancer. Further research is needed to fully understand the role of RCN2 in cellular processes and its potential as a drug target.

Protein Name: Reticulocalbin 2

Functions: Not known. Binds calcium

More Common Targets

RCN3 | RCOR1 | RCOR2 | RCOR3 | RCSD1 | RCVRN | RD3 | RD3L | RDH10 | RDH11 | RDH12 | RDH13 | RDH14 | RDH16 | RDH5 | RDH8 | RDM1 | RDUR | RDX | RDXP2 | Reactive oxygen species (ROS) | REC114 | REC8 | RECK | RECQL | RECQL4 | RECQL5 | REELD1 | REEP1 | REEP2 | REEP3 | REEP4 | REEP5 | REEP6 | REG1A | REG1B | REG1CP | REG3A | REG3G | REG4 | REL | REL-DT | RELA | Relaxin | Relaxin receptor | RELB | RELCH | RELL1 | RELL2 | RELN | RELT | REM1 | REM2 | REN | RENBP | REP15 | Repeat-binding factor | REPIN1 | Replication factor C | Replication Protein A Complex (RPA) | REPS1 | REPS2 | RER1 | RERE | REREP3 | RERG | RERGL | RESF1 | RESP18 | REST | RET | Retinoid acid receptor | Retinoid RXR receptor | Retinol dehydrogenase | RETN | RETNLB | RETREG1 | RETREG2 | RETREG3 | RETSAT | REV1 | REV3L | Reverse transcriptase (Telomerase) | REX1BD | REXO1 | REXO1L1P | REXO1L2P | REXO1L6P | REXO1L8P | REXO2 | REXO4 | REXO5 | RFC1 | RFC2 | RFC3 | RFC4 | RFC5 | RFESD | RFESDP1 | RFFL