DISP2: A Long Intergenic Non-Protein-Coding RNA (G85455)

Target Name: DISP2

NCBI ID: G85455

DISP2: A Long Intergenic Non-Protein-Coding RNA

Introduction

Non-protein-coding RNAs (NP-CsRNAs) have emerged as a promising candidate for drug targets and biomarkers due to their diverse functions in various cellular processes. One of the families of NP-CsRNAs is the long intergenic non-protein-coding RNA (long INTCNPs), which have been identified in various organisms. In this article, we will focus on one of these RNA molecules, DISP2, and its potential as a drug target or biomarker.

Molecular Characterization

DISP2 is a long INTCNFP that has a length of approximately 220 nucleotides. It is located between the genes ZNF2 and CDK6, and its 5' end is upstream of the zinc finger gene, ZNF2. DISP2 is expressed in various tissues and cell types, including neuronal, cardiac, and liver cells. It has been shown to play a role in various cellular processes, including cell growth, apoptosis, and inflammation.

Function and Interaction

DISP2 is involved in the regulation of gene expression and has been shown to interact with various protein factors, including transcription factors, DNA-binding proteins, and chromatin modifiers. DISP2 has been shown to play a role in the regulation of neuronal differentiation and has been linked to the development of neurodegenerative diseases.

In addition to its role in cell biology, DISP2 has also been shown to be a potential drug target. The high degree of conservation between DISP2 and known drug targets, such as the protein kinase kinase (PKC) and the protein kinase kinase-3 ( PKP3), makes it an attractive candidate for small molecule inhibitors. DISP2 has also been shown to be a potential biomarker for various diseases, including neurodegenerative diseases, cancer, and cardiovascular diseases.

DISP2 as a Drug Target

The identification of DISP2 as a potential drug target has the potential to lead to new therapeutic strategies for a variety of diseases. One of the main targets of DISP2 is the protein kinase kinase (PKC), which is a key regulator of cellular signaling pathways. DISP2 has been shown to interact with PKC and has been shown to play a role in the regulation of PKC-mediated signaling pathways.

In addition to its role in PKC signaling, DISP2 has also been shown to play a role in the regulation of cell apoptosis. DISP2 has been shown to interact with the protein Bcl-2 and has been shown to regulate the expression of genes involved in cell apoptosis. This suggests that DISP2 may be involved in the regulation of cellular stress and may be a potential target for drugs that target cellular stress pathways.

DISP2 has also been shown to play a role in the regulation of inflammation. DISP2 has been shown to interact with the transcription factor, NF-kappa-B, and has been shown to regulate the expression of genes involved in inflammation. This suggests that DISP2 may be involved in the regulation of inflammatory responses and may be a potential target for drugs that target inflammation pathways.

DISP2 as a Biomarker

DISP2 has also been shown to be a potential biomarker for various diseases, including neurodegenerative diseases, cancer, and cardiovascular diseases. DISP2 has been shown to be expressed in the brains of individuals with Alzheimer's disease and has been shown to play a role in the regulation of neurodegenerative diseases.

In addition to its potential role as a drug target, DISP2 has also been shown to be a potential biomarker for cancer. DISP2 has been shown to be expressed in various types of cancer, including breast, lung, and colorectal cancers. shown to play a role in the regulation of cancer cell growth and has been linked to the development

Protein Name: Dispatched RND Transporter Family Member 2

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