SNX4: A Protein Involved in Tissue Development and Maintenance
SNX4: A Protein Involved in Tissue Development and Maintenance
SNX4, or Sorting nexin 4, is a protein that is expressed in various tissues throughout the body. It is a member of the superfamily of coiled-coil proteins, which are characterized by the presence of a coiled-coil region that can interact with other proteins. One of the unique features of SNX4 is its ability to interact with the protein ZNF2, which is known to play a role in the development and maintenance of tissues.
SNX4 has been shown to be involved in a number of physiological processes in the body, including cell signaling, tissue structure, and cellular processes that are important for the development and maintenance of tissues. It is also of interest as a potential drug target, due to its involvement in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders.
One of the key functions of SNX4 is its role in the development and maintenance of tissues. SNX4 is a member of the superfamily of coiled-coil proteins, which are characterized by the presence of a coiled-coil region that can interact with other proteins. This interaction between SNX4 and other proteins allows it to play a role in the development and maintenance of tissues.
For example, SNX4 has been shown to be involved in the development and maintenance of tissues that are important for the development of organs, such as hearts and kidneys. Studies have shown that SNX4 is involved in the regulation of cell proliferation and differentiation, as well as the formation of tissues that are important for the development of organs.
In addition to its role in tissue development, SNX4 is also involved in the regulation of cellular processes that are important for the maintenance of tissues. For example, studies have shown that SNX4 is involved in the regulation of cell signaling, as well as the production of cellular organelles, such as mitochondria and endoplasmic reticulum.
SNX4 is also of interest as a potential drug target, due to its involvement in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders. For example, studies have shown that SNX4 is involved in the development and progression of cancer, and that it is a potential target for anti-cancer drugs. In addition, SNX4 is also involved in the development of neurodegenerative diseases, such as Alzheimer's disease, and has been shown to play a role in the regulation of cellular processes that are important for the maintenance of these diseases.
In conclusion, SNX4 is a protein that is involved in a number of physiological processes in the body, including cell signaling, tissue structure, and cellular processes that are important for the development and maintenance of tissues. It is also of interest as a potential drug target, due to its involvement in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders. Further research is needed to fully understand the role of SNX4 in these processes, as well as its potential as a drug target.
Protein Name: Sorting Nexin 4
Functions: Involved in the regulation of endocytosis and in several stages of intracellular trafficking (PubMed:12668730, PubMed:17994011, PubMed:32513819, PubMed:33468622). Plays a role in recycling endocytosed transferrin receptor and prevent its degradation (PubMed:17994011). Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A (PubMed:32513819, PubMed:33468622)
More Common Targets
SNX5 | SNX6 | SNX7 | SNX8 | SNX9 | SOAT1 | SOAT2 | SOBP | SOCAR | SOCS1 | SOCS2 | SOCS2-AS1 | SOCS3 | SOCS3-DT | SOCS4 | SOCS5 | SOCS5P5 | SOCS6 | SOCS7 | SOD1 | SOD2 | SOD2-OT1 | SOD3 | Sodium channel | Sodium-Glucose Cotransporter (SGLT) | Sodium-potassium-calcium exchanger | SOGA1 | SOGA3 | SOHLH1 | SOHLH2 | Soluble (cytosolic) protein tyrosine phosphatases | Soluble guanylyl cyclase | Solute Carrier Family 12 | Solute carrier family 29 member | Somatostatin receptor | SON | SORBS1 | SORBS2 | SORBS3 | SORCS1 | SORCS2 | SORCS3 | SORCS3-AS1 | SORD | SORD2P | SORL1 | SORT1 | Sorting and assembly machinery complex | Sorting nexin | SOS1 | SOS2 | SOSS complex | SOST | SOSTDC1 | SOWAHA | SOWAHB | SOWAHC | SOWAHD | SOX1 | SOX1-OT | SOX10 | SOX11 | SOX12 | SOX13 | SOX14 | SOX15 | SOX17 | SOX18 | SOX2 | SOX2-OT | SOX21 | SOX21-AS1 | SOX3 | SOX30 | SOX30P1 | SOX4 | SOX5 | SOX5-AS1 | SOX6 | SOX7 | SOX8 | SOX9 | SOX9-AS1 | SP1 | SP100 | SP110 | SP140 | SP140L | SP2 | SP2-AS1 | SP3 | SP3P | SP4 | SP5 | SP6 | SP7 | SP8 | SP9 | SPA17 | SPAAR
