SOS2: A Potential Drug Target and Biomarker for Son of Sevenless Homolog 2-mediated Diseases
SOS2: A Potential Drug Target and Biomarker for Son of Sevenless Homolog 2-mediated Diseases
Son of Sevenless Homolog 2 (SOS2) is a gene that has been identified as a potential drug target and biomarker for a variety of diseases. SOS2 is a member of the Superfamily of Transmembrane Protein Serine 1 (SMP) gene family, which is known for its role in cell signaling and development. SOS2 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
One of the key features of SOS2 is its ability to interact with and regulate the activity of other genes, including son of sevenless homolog 1 (SOS1). SOS1 is also a member of the SMP gene family and has been shown to play a role in the development and progression of various diseases. The SOS2-SOS1 interaction has been shown to promote the development of SOS2-mediated diseases.
SOS2 has also been shown to interact with and regulate the activity of the transcription factor, p53. p53 is a well-known gene that plays a critical role in the regulation of gene expression and has been shown to play a role in the development and progression of various diseases. The SOS2-p53 interaction has been shown to promote the development of SOS2-mediated diseases.
In addition to its interactions with son of sevenless homolog 1 and p53, SOS2 has also been shown to interact with and regulate the activity of the protein, heat shock protein 70 (Hsp70). Hsp70 is a protein that is involved in the regulation of various cellular processes, including stress responses and protein folding. The SOS2-Hsp70 interaction has been shown to promote the development of SOS2-mediated diseases.
SOS2 has also been shown to interact with and regulate the activity of the protein, IISP (IISP) gene. IISP is a protein that is involved in the regulation of various cellular processes, including cell signaling and development. The SOS2-IISP interaction has has been shown to promote the development of SOS2-mediated diseases.
In conclusion, SOS2 is a gene that has been shown to interact with and regulate the activity of multiple genes, including son of sevenless homolog 1, p53, Hsp70, and IISP. These interactions suggest that SOS2 may be a drug target and biomarker for a variety of diseases. Further research is needed to confirm these findings and to determine the full scope of SOS2's potential role in disease.
Protein Name: SOS Ras/Rho Guanine Nucleotide Exchange Factor 2
Functions: Promotes the exchange of Ras-bound GDP by GTP
More Common Targets
SOSS complex | SOST | SOSTDC1 | SOWAHA | SOWAHB | SOWAHC | SOWAHD | SOX1 | SOX1-OT | SOX10 | SOX11 | SOX12 | SOX13 | SOX14 | SOX15 | SOX17 | SOX18 | SOX2 | SOX2-OT | SOX21 | SOX21-AS1 | SOX3 | SOX30 | SOX30P1 | SOX4 | SOX5 | SOX5-AS1 | SOX6 | SOX7 | SOX8 | SOX9 | SOX9-AS1 | SP1 | SP100 | SP110 | SP140 | SP140L | SP2 | SP2-AS1 | SP3 | SP3P | SP4 | SP5 | SP6 | SP7 | SP8 | SP9 | SPA17 | SPAAR | SPACA1 | SPACA3 | SPACA4 | SPACA5 | SPACA6 | SPACA6-AS1 | SPACA7 | SPACA9 | SPACDR | SPAG1 | SPAG11A | SPAG11B | SPAG16 | SPAG16-DT | SPAG17 | SPAG4 | SPAG5 | SPAG5-AS1 | SPAG6 | SPAG7 | SPAG8 | SPAG9 | SPAM1 | SPANXA1 | SPANXA2-OT1 | SPANXB1 | SPANXB2 | SPANXC | SPANXD | SPANXN1 | SPANXN2 | SPANXN3 | SPANXN4 | SPANXN5 | SPARC | SPARCL1 | SPART | SPART-AS1 | SPAST | SPATA1 | SPATA12 | SPATA13 | SPATA13-AS1 | SPATA16 | SPATA17 | SPATA18 | SPATA19 | SPATA2 | SPATA20 | SPATA20P1 | SPATA21