Target Name: SPACA1
NCBI ID: G81833
Other Name(s): SAMP32 | sperm acrosome associated 1 | SACA1_HUMAN | Sperm acrosome associated 1 | sperm acrosomal membrane-associated protein 32 | Sperm acrosome membrane-associated protein 1 | Sperm acrosomal membrane-associated protein 32

SPACA1: A Potential Drug Target and Biomarker for Neurodegenerative Disorders

SPACA1 (SAMP32) is a gene that has been identified as a potential drug target and biomarker for various diseases, including heart disease, diabetes, and neurodegenerative disorders. The SAMP32 gene is a member of the S1P (Sirtuin) family, which is known for Its role in various cellular processes, including DNA repair, stress response, and inflammation.

SPACA1 is a non-coding RNA molecule that is expressed in a variety of tissues and cells in the body. It is a key regulator of gene expression in many cell types, and has been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

One of the unique features of SPACA1 is its ability to interact with other genes and molecules. It has been shown to form complex with various protein partners, including the transcription factor p53, which is known for its role in the regulation of cellular processes such as DNA damage repair and apoptosis.

SPACA1 has also been shown to play a role in the regulation of cellular signaling pathways. It has been shown to interact with the protein kinase A1 (PKA1), which is known for its role in the regulation of cellular signaling pathways such as protein kinase signaling . This interaction between SPACA1 and PKA1 suggests that SPACA1 may be a potential drug target for diseases that are characterized by the disruption of cellular signaling pathways.

SPACA1 has also been shown to be involved in the regulation of cellular apoptosis. It has been shown to play a role in the regulation of cell death in various cell types, including neurons and immune cells. This suggests that SPACA1 may be a potential drug target for diseases that are characterized by the disruption of cellular apoptosis.

In addition to its potential drug target and biomarker properties, SPACA1 is also of interest due to its potential role in the development of neurodegenerative disorders. The S1P family has been shown to play a role in the regulation of neurodegenerative disorders, and SPACA1 is thought to be involved in the regulation of cellular processes that are relevant to the development and progression of these disorders.

Overall, SPACA1 is a gene that has the potential to be a drug target and biomarker for a variety of diseases. Further research is needed to determine its exact role in the regulation of cellular processes and its potential as a drug target.

Protein Name: Sperm Acrosome Associated 1

Functions: Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis (By similarity). Important for male fertility (PubMed:11870081)

More Common Targets

SPACA3 | SPACA4 | SPACA5 | SPACA6 | SPACA6-AS1 | SPACA7 | SPACA9 | SPACDR | SPAG1 | SPAG11A | SPAG11B | SPAG16 | SPAG16-DT | SPAG17 | SPAG4 | SPAG5 | SPAG5-AS1 | SPAG6 | SPAG7 | SPAG8 | SPAG9 | SPAM1 | SPANXA1 | SPANXA2-OT1 | SPANXB1 | SPANXB2 | SPANXC | SPANXD | SPANXN1 | SPANXN2 | SPANXN3 | SPANXN4 | SPANXN5 | SPARC | SPARCL1 | SPART | SPART-AS1 | SPAST | SPATA1 | SPATA12 | SPATA13 | SPATA13-AS1 | SPATA16 | SPATA17 | SPATA18 | SPATA19 | SPATA2 | SPATA20 | SPATA20P1 | SPATA21 | SPATA22 | SPATA24 | SPATA25 | SPATA2L | SPATA3 | SPATA3-AS1 | SPATA31A1 | SPATA31A2 | SPATA31A3 | SPATA31A5 | SPATA31A6 | SPATA31A7 | SPATA31C1 | SPATA31C2 | SPATA31D1 | SPATA31D3 | SPATA31E1 | SPATA32 | SPATA33 | SPATA4 | SPATA41 | SPATA42 | SPATA45 | SPATA46 | SPATA48 | SPATA5 | SPATA5L1 | SPATA6 | SPATA6L | SPATA7 | SPATA8 | SPATA8-AS1 | SPATA9 | SPATC1 | SPATC1L | SPATS1 | SPATS2 | SPATS2L | SPC24 | SPC25 | SPCS1 | SPCS2 | SPCS2P4 | SPCS3 | SPDEF | SPDL1 | SPDYA | SPDYC | SPDYE1 | SPDYE18