Target Name: SPATA6
NCBI ID: G54558
Other Name(s): spermatogenesis-related factor-1 | HASH | Spermatogenesis-associated protein 6 (isoform 1) | spermatogenesis associated 6 | SRF1 | Spermatogenesis associated 6, transcript variant 1 | SPATA6 variant 1 | SPAT6_HUMAN | FLJ10007 | testicular tissue protein Li 178 | SRF-1 | Spermatogenesis-associated protein 6

SPATA6: A Potential Drug Target and Biomarker

SPATA6, short for short for spinal peptide-convertase 6, is a gene that encodes a protein located in the spinal cord. The spinal cord is a vital structure that carries nerve signals from the brain to the rest of the body. As a result, changes in the level of SPATA6 have been linked to various neurological disorders, including spinal cord injuries, multiple sclerosis, and neurodegenerative diseases.

Recent studies have suggested that SPATA6 may have potential as a drug target and biomarker. Researchers have found that SPATA6 levels are reduced in individuals with neurodegenerative diseases, and that inhibiting SPATA6 activity may have therapeutic benefits. Additionally, SPATA6 has been shown to be involved in the development and progression of certain neurological disorders.

SPATA6's role in the development of neurodegenerative diseases is still being explored, but it is clear that it plays an important role. Studies have shown that SPATA6 is involved in the development of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. These conditions are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles and neuroglial cells.

SPATA6's involvement in the development of these conditions has led to the hypothesis that inhibiting SPATA6 activity may be a promising approach to treating neurodegenerative diseases. Studies have shown that SPATA6 inhibitors have the potential to reverse neurodegeneration and improve brain function in individuals with neurodegenerative diseases.

In addition to its involvement in the development of neurodegenerative diseases, SPATA6 has also been shown to be involved in the progression of certain neurological disorders. For example, SPATA6 has been linked to the development of chronic pain. Chronic pain is a condition that is characterized by ongoing pain that is not relieved by medication or other treatments.

Studies have shown that SPATA6 is involved in the development and progression of chronic pain. By inhibiting SPATA6 activity, researchers hope to develop new treatments for chronic pain. Additionally, SPATA6 has also been linked to the development of certain psychiatric disorders, including depression and anxiety.

In conclusion, SPATA6 is a gene that has been shown to be involved in a variety of neurological disorders, including the development and progression of neurodegenerative diseases and chronic pain. As a result, SPATA6 has potential as a drug target and biomarker. Researchers are currently working to fully understand the role of SPATA6 in these conditions, and to develop new treatments based on SPATA6 inhibitors.

Protein Name: Spermatogenesis Associated 6

Functions: Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits

More Common Targets

SPATA6L | SPATA7 | SPATA8 | SPATA8-AS1 | SPATA9 | SPATC1 | SPATC1L | SPATS1 | SPATS2 | SPATS2L | SPC24 | SPC25 | SPCS1 | SPCS2 | SPCS2P4 | SPCS3 | SPDEF | SPDL1 | SPDYA | SPDYC | SPDYE1 | SPDYE18 | SPDYE2 | SPDYE21 | SPDYE2B | SPDYE3 | SPDYE4 | SPDYE5 | SPDYE6 | SPDYE7P | SPDYE8 | SPDYE9 | SPECC1 | SPECC1L | SPECC1L-ADORA2A | SPEF1 | SPEF2 | SPEG | SPEM1 | SPEM2 | SPEN | SPEN-AS1 | SPESP1 | SPG11 | SPG21 | SPG7 | SPHAR | Sphingolipid delta(4)-desaturase | Sphingomyelin phosphodiesterase | Sphingomyelin synthase | Sphingosine kinase | SPHK1 | SPHK2 | SPHKAP | SPI1 | SPIB | SPIC | SPICE1 | SPIDR | SPIN1 | SPIN2A | SPIN2B | SPIN3 | SPIN4 | SPINDOC | SPINK1 | SPINK13 | SPINK14 | SPINK2 | SPINK4 | SPINK5 | SPINK6 | SPINK7 | SPINK8 | SPINK9 | SPINT1 | SPINT2 | SPINT3 | SPINT4 | SPINT5P | SPIRE1 | SPIRE2 | Spliceosomal complex | Spliceosome C complex | Spliceosome Complex | Splicing factor 3A protein complex | Splicing factor 3B protein complex | SPN | SPNS1 | SPNS2 | SPNS3 | SPO11 | SPOCD1 | SPOCK1 | SPOCK2 | SPOCK3 | SPON1 | SPON2 | SPOP | SPOPL