Target Name: SPCS1
NCBI ID: G28972
Other Name(s): YJR010C-A | microsomal signal peptidase 12 kDa subunit | SPase 12 kDa subunit | signal peptidase complex subunit 1 homolog | signal peptidase complex subunit 1 | OTTHUMP00000206959 | Signal peptidase 12kDa | signal peptidase complex 12 kDa subunit | SPC12 | SPCS1_HUMAN | Signal peptidase complex subunit 1 | SPC1 | Signal peptidase complex subunit 1 homolog (S. cerevisiae) | signal peptidase 12kDa | Microsomal signal peptidase 12 kDa subunit | HSPC033

SPCS1: A Protein Involved in Many Physiological Processes and Potential Drug Target

SPCS1 (SPC1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and function of cells. SPCS1 is unique because it is able to form a stable complex with the protein known as p120GAP, which is a known regulator of the stress response.

SPCS1 has been shown to play a role in a variety of physiological processes in the body, including the regulation of inflammation, cell division, and the stress response. It is also involved in the development and maintenance of various diseases, including cancer.

One of the most promising aspects of SPCS1 is its potential as a drug target. Because it is involved in so many important processes in the body, it is a promising target for the development of new treatments for a wide range of diseases.

SPCS1 is also a potential biomarker for a variety of diseases. Because it is involved in the regulation of many physiological processes, it is possible that changes in the level of SPCS1 expression could be an indicator of certain diseases. This makes it an attractive target for the development of diagnostic tools and therapies.

In conclusion, SPCS1 is a protein that is widely expressed in various tissues throughout the body and is involved in a variety of important physiological processes. Its unique ability to form a stable complex with the protein known as p120GAP makes it a promising target for the development of new treatments for a wide range of diseases. Additionally, its involvement in the regulation of many physiological processes makes it a potential biomarker for a variety of diseases. Further research is needed to fully understand the role of SPCS1 in the body and its potential as a drug target and biomarker.

Protein Name: Signal Peptidase Complex Subunit 1

Functions: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369). Dispensable for SPC enzymatic activity (By similarity)

More Common Targets

SPCS2 | SPCS2P4 | SPCS3 | SPDEF | SPDL1 | SPDYA | SPDYC | SPDYE1 | SPDYE18 | SPDYE2 | SPDYE21 | SPDYE2B | SPDYE3 | SPDYE4 | SPDYE5 | SPDYE6 | SPDYE7P | SPDYE8 | SPDYE9 | SPECC1 | SPECC1L | SPECC1L-ADORA2A | SPEF1 | SPEF2 | SPEG | SPEM1 | SPEM2 | SPEN | SPEN-AS1 | SPESP1 | SPG11 | SPG21 | SPG7 | SPHAR | Sphingolipid delta(4)-desaturase | Sphingomyelin phosphodiesterase | Sphingomyelin synthase | Sphingosine kinase | SPHK1 | SPHK2 | SPHKAP | SPI1 | SPIB | SPIC | SPICE1 | SPIDR | SPIN1 | SPIN2A | SPIN2B | SPIN3 | SPIN4 | SPINDOC | SPINK1 | SPINK13 | SPINK14 | SPINK2 | SPINK4 | SPINK5 | SPINK6 | SPINK7 | SPINK8 | SPINK9 | SPINT1 | SPINT2 | SPINT3 | SPINT4 | SPINT5P | SPIRE1 | SPIRE2 | Spliceosomal complex | Spliceosome C complex | Spliceosome Complex | Splicing factor 3A protein complex | Splicing factor 3B protein complex | SPN | SPNS1 | SPNS2 | SPNS3 | SPO11 | SPOCD1 | SPOCK1 | SPOCK2 | SPOCK3 | SPON1 | SPON2 | SPOP | SPOPL | SPOUT1 | SPP1 | SPP2 | SPPL2A | SPPL2B | SPPL2C | SPPL3 | SPR | SPRED1 | SPRED2 | SPRED3 | SPRING1 | SPRN