SPOUT1: A Potential Drug Target and Biomarker (G51490)

Target Name: SPOUT1

NCBI ID: G51490

SPOUT1: A Potential Drug Target and Biomarker

SPOUT1 (SPOUT1-like gene 1) is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The gene is located on chromosome 12 and encodes a protein known as SPOUT1, which is a protein that is expressed in many different tissues and cells in the body.

SPOUT1 is involved in a variety of cellular processes that are important for normal development and function. It is a key regulator of cell adhesion and has been shown to play a role in the development and progression of various diseases.

One of the most promising aspects of SPOUT1 is its potential as a drug target. By blocking the activity of SPOUT1, researchers can prevent the cells from functioning properly, which can lead to the development of diseases. This is because SPOUT1 is involved in the regulation of many cellular processes that are important for normal function, so blocking its activity can have a wide range of effects on the body.

SPOUT1 has also been shown to be a potential biomarker for several diseases. For example, SPOUT1 has been shown to be overexpressed in many types of cancer, which suggests that it may be a useful indicator of the disease. Additionally, SPOUT1 has been shown to be overexpressed in neurodegenerative diseases, which may make it an attractive target for new treatments.

In addition to its potential as a drug target and biomarker, SPOUT1 is also of interest to researchers because of its location on chromosome 12. This suggests that it may be a useful target for drugs that can modify gene expression or disrupt the function of specific genes.

Overall, SPOUT1 is a gene that has the potential to be a valuable drug target and biomarker for a wide range of diseases. Further research is needed to fully understand its role and to develop new treatments based on its properties.

Protein Name: SPOUT Domain Containing Methyltransferase 1

Functions: Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase (PubMed:20813266, PubMed:25657325). Also involved in chromosome alignment (PubMed:20813266). May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis (PubMed:25657325). Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level (PubMed:28431233)

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