SRI: A Protein Involved in Brain Development and Function (G6717)
SRI: A Protein Involved in Brain Development and Function
SRI (22 kDa protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is made up of 22 amino acid residues and has a calculated molecular weight of 23.9 kDa.
One of the unique features of SRI is its expression pattern. It is predominantly expressed in the brain, where it is found in the enolized neuronal nuclei. It is also expressed in the endoplasmic reticulum and in the cytoplasm of neuronal cells.
SRI has been shown to play a role in a number of cellular processes, including cell signaling, neurotransmitter release, and stress response. It is involved in the regulation of several signaling pathways, including the insulin/IGF-1 signaling pathway, the TGF- 尾 signaling pathway, and the Wnt signaling pathway.
SRI has also been shown to be involved in the regulation of cellular processes that are important for brain development and function, such as synaptic plasticity and learning. It is thought to play a role in the regulation of synaptic strength, as well as the modulation of neurotransmitter release and neuronal excitability.
SRI is also of interest as a potential drug target. Its unique expression pattern in the brain makes it an attractive target for small molecule inhibitors, which can be used to disrupt its functions and treat a variety of neurological and psychiatric disorders.
In addition to its potential as a drug target, SRI is also of interest as a biomarker. Its expression pattern is altered in a number of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. Therefore, it may be used as a diagnostic or therapeutic target in these disorders.
In conclusion, SRI is a protein that is expressed in various tissues throughout the body and is involved in a number of cellular processes. Its unique expression pattern in the brain makes it an attractive target for small molecule inhibitors, as well as a potential drug and biomarker. Further research is needed to fully understand its functions and potential uses in medicine.
Protein Name: Sorcin
Functions: Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels
More Common Targets
SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX | SRPX2 | SRR | SRRD | SRRM1 | SRRM1P1 | SRRM2 | SRRM2-AS1 | SRRM3 | SRRM4 | SRRM5 | SRRT | SRSF1 | SRSF10 | SRSF11 | SRSF12 | SRSF2 | SRSF3 | SRSF3P2 | SRSF4 | SRSF5 | SRSF6 | SRSF6P1 | SRSF7 | SRSF8 | SRSF9 | SRXN1 | SRY | SS18 | SS18L1 | SS18L2 | SSB | SSBP1 | SSBP2 | SSBP3 | SSBP3-AS1 | SSBP3P2 | SSBP4 | SSC4D | SSC5D | SSH1 | SSH2 | SSH3 | SSMEM1 | SSNA1 | SSPN | SSPOP | SSR1 | SSR1P2 | SSR2 | SSR3 | SSR4 | SSR4P1 | SSRP1 | SST | SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 | SSTR5-AS1 | SSU72 | SSU72L2 | SSU72P1 | SSU72P8 | SSUH2 | SSX1 | SSX2 | SSX2IP | SSX3 | SSX4 | SSX5 | SSX6P | SSX7 | SSX8P | SSX9P | SSXP10 | SSXP5 | ST13 | ST13P16 | ST13P18 | ST13P20