HSP70: A Protein Involved in Cellular Stress Response (G6767)

Target Name: ST13

NCBI ID: G6767

HSP70: A Protein Involved in Cellular Stress Response

ST13 (F10A1_HUMAN), also known as HSP70, is a protein that is expressed in various tissues throughout the body, including the heart, lungs, kidneys, and liver. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in response to increased temperatures, such as those caused by stress or exercise.

HSP70 is a protein that is involved in a variety of cellular processes, including the regulation of protein synthesis and degradation, DNA replication and repair, and cell signaling. It is also involved in the detoxification of harmful substances, such as drugs and radiation.

One of the unique features of HSP70 is its ability to form a stable complex with other proteins, known as cochymers. These complexes are thought to play a role in the regulation of cellular processes, including cell signaling and protein-protein interactions.

HSP70 has also been shown to be involved in the regulation of cellular stress responses. When cells are exposed to stressors, such as drugs or radiation, HSP70 can help to prevent the damage caused by these stressors by forming a stable complex with other proteins.

Despite its involvement in cellular stress responses, HSP70 is not a drug target or biomarker. However, research into its functions and interactions with other proteins may provide insights into the mechanisms underlying cellular stress responses and the potential therapeutic uses of drugs that target these processes.

Overall, HSP70 is a protein that is expressed in various tissues throughout the body and is involved in a variety of cellular processes. While it is not currently a drug target or biomarker, research into its functions and interactions with other proteins may provide insights into the mechanisms underlying cellular stress responses and the potential therapeutic uses of drugs that target these processes.

Protein Name: ST13 Hsp70 Interacting Protein

Functions: One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity)

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