Understanding The Role of ST8SIA6 in Cancer and Autoimmune Disorders

Target Name: ST8SIA6

NCBI ID: G338596

Understanding The Role of ST8SIA6 in Cancer and Autoimmune Disorders

ST8SIA6 (alpha-2,8-sialyltransferase 8F) is a protein that is expressed in a variety of tissues throughout the body, including the brain, heart, liver, and muscle. It is a type of enzyme that is involved in the transfer of sialic acid to the cell surface, which is a type of carbohydrate found on the surface of many types of cells. This protein is of particular interest as a potential drug target or biomarker because of its role in the development and progression of a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of ST8SIA6 is its role in the development of cancer. Many studies have shown that high levels of ST8SIA6 are associated with the development of various types of cancer, including breast, ovarian, and prostate cancer. This is because ST8SIA6 has been shown to promote the growth and survival of cancer cells. In addition, ST8SIA6 has also been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Another potential function of ST8SIA6 is its role in the development of autoimmune disorders. Many autoimmune disorders, such as rheumatoid arthritis, lupus, and multiple sclerosis, involve the immune system attacking the body's own tissues. ST8SIA6 has been shown to be involved in the development of these disorders by promoting the production of immune cells that contribute to the immune response.

In addition to its potential functions as a drug target or biomarker, ST8SIA6 is also of interest to researchers because of its structure and the events that occur during its function. The structure of ST8SIA6 has been studied extensively, and it is known to have a unique fold that allows it to interact with other proteins and molecules. This interaction with other molecules is thought to play a role in the functions of ST8SIA6. In addition, the events that occur during ST8SIA6's function have also been studied extensively, and it is known to play a role in a number of cellular processes, including cell signaling, protein synthesis, and inflammation.

Overall, ST8SIA6 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Its role in the development and progression of cancer, neurodegenerative diseases, and autoimmune disorders, as well as its unique structure and the events that occur during its function, make it an attractive target for further research. While further research is needed to fully understand the functions of ST8SIA6 and its potential as a drug or biomarker, its study is likely to continue to be an important area of research in the years to come.

Protein Name: ST8 Alpha-N-acetyl-neuraminide Alpha-2,8-sialyltransferase 6

Functions: Alpha-2,8-sialyltransferase that prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc-alpha-2,3(6)-Gal sequence at the non-reducing end of their carbohydrate groups

More Common Targets