SPSB1: A Protein Involved in Intracellular Signaling and Tissue Growth

Target Name: SPSB1

NCBI ID: G80176

SPSB1: A Protein Involved in Intracellular Signaling and Tissue Growth

SPSB1 (SPRY domain-containing SOCS box protein 1) is a protein that is expressed in various tissues throughout the body. It is a member of the SPRY family of proteins, which are known for their role in intracellular signaling. SPSB1 is characterized by the presence of a SPRY domain, which is a unique type of protein domain that is found in a variety of proteins that are involved in intracellular signaling.

The SPSB1 protein is involved in a number of different cellular processes in the body, including the regulation of cell growth, differentiation, and survival. It is also involved in the development and maintenance of tissues, such as the brain and nervous system.

SPSB1 is a potential drug target, due to its involvement in a number of important cellular processes. It is also a potential biomarker, as it can be used to diagnose and monitor a variety of diseases.

One of the key functions of SPSB1 is its role in intracellular signaling. It is involved in the regulation of a variety of signaling pathways, including the TGF-β pathway and the Wnt pathway. This means that SPSB1 plays a key role in the development and maintenance of tissues, as well as in the regulation of cellular processes that are important for tissue growth and differentiation.

In addition to its role in intracellular signaling, SPSB1 is also involved in the regulation of cellular processes that are important for the development and maintenance of tissues. It is involved in the regulation of cell adhesion, as well as the development and maintenance of tissues such as the brain and nervous system.

SPSB1 is also involved in the regulation of cellular processes that are important for the regulation of ion channels and the conduction of electrical signals within cells. This is important for the regulation of a variety of cellular processes, including the regulation of muscle contractions and the regulation of neural signals.

SPSB1 is a protein that is expressed in a variety of tissues throughout the body, and it is involved in a number of different cellular processes that are important for the development and maintenance of tissues. It is a potential drug target and biomarker, due to its involvement in intracellular signaling and the regulation of cellular processes that are important for tissue growth and maintenance. Further research is needed to fully understand the role of SPSB1 in these processes and its potential as a drug target and biomarker.

Protein Name: SplA/ryanodine Receptor Domain And SOCS Box Containing 1

Functions: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820, PubMed:21199876). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:21199876). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed:21199876)

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