Target Name: SRFBP1
NCBI ID: G153443
Other Name(s): BUD22 homolog | p49/STRAP | STRAP | SRFB1_HUMAN | serum response factor binding protein 1 | Serum response factor binding protein 1 | P49 | Rlb1 | SRF-dependent transcription regulation-associated protein | Serum response factor-binding protein 1 | FLJ25286 | SRF-dependent transcription regulation associated protein | BUD22

SRFBP1: A Potential Drug Target and Biomarker for Various Diseases

SRFBP1 (BUD22 homolog) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an intriguing target for researchers to investigate.

TheSRFBP1 gene is located on chromosome 12p36 and encodes a protein known as BUD22. BUD22 is a post-transcriptionally modified protein, which means that it is modified by processes that occur after it is synthesized. These modifications can alter the structure and function of the protein , making it an attractive target for drugs that want to interfere with its activity.

One of the key features of SRFBP1 is its ability to interact with other proteins, particularly with the protein known as TCF7L. TCF7L is a transcription factor that plays a role in the development and maintenance of tissues, including brain and spinal cord. It has been shown to be involved in various neurological and psychiatric diseases, including Alzheimer's disease, Parkinson's disease, and schizophrenia.

Research has also suggested that SRFBP1 may be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These diseases are characterized by progressive loss of brain cells and an increased risk of cognitive decline and other symptoms.

In addition to its potential role in neurodegenerative diseases, SRFBP1 has also been shown to be involved in the development and progression of certain autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. These disorders are characterized by the immune system attacking the body's own tissues, leading to inflammation and joint damage.

The SRFBP1 gene has also been shown to be involved in the development of various types of cancer, including breast, ovarian, and prostate cancer. These cancers are characterized by the formation of tumors, which can then spread to other parts of the body.

The potential drug targets for SRFBP1 are vast, as the gene has been shown to be involved in so many different diseases and conditions. It is likely that future research will uncover new ways to target the protein and potentially lead to new treatments for a range of diseases.

In addition to its potential as a drug target, SRFBP1 has also been shown to be a potential biomarker for various diseases. The ability of the protein to interact with other proteins and its involvement in the development and progression of various diseases make it an attractive candidate for use as a diagnostic or predictive marker.

Overall, SRFBP1 (BUD22 homolog) is a gene that has the potential to be a drug target or biomarker for a wide range of diseases. Its unique structure and function make it an intriguing target for researchers to investigate, and its potential as a treatment or diagnostic tool is sure to continue to attract attention in the years to come.

Protein Name: Serum Response Factor Binding Protein 1

Functions: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity)

More Common Targets

SRGAP1 | SRGAP2 | SRGAP2B | SRGAP2C | SRGAP2D | SRGAP3 | SRGN | SRI | SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX | SRPX2 | SRR | SRRD | SRRM1 | SRRM1P1 | SRRM2 | SRRM2-AS1 | SRRM3 | SRRM4 | SRRM5 | SRRT | SRSF1 | SRSF10 | SRSF11 | SRSF12 | SRSF2 | SRSF3 | SRSF3P2 | SRSF4 | SRSF5 | SRSF6 | SRSF6P1 | SRSF7 | SRSF8 | SRSF9 | SRXN1 | SRY | SS18 | SS18L1 | SS18L2 | SSB | SSBP1 | SSBP2 | SSBP3 | SSBP3-AS1 | SSBP3P2 | SSBP4 | SSC4D | SSC5D | SSH1 | SSH2 | SSH3 | SSMEM1 | SSNA1 | SSPN | SSPOP | SSR1 | SSR1P2 | SSR2 | SSR3 | SSR4 | SSR4P1 | SSRP1 | SST | SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 | SSTR5-AS1 | SSU72 | SSU72L2 | SSU72P1 | SSU72P8 | SSUH2 | SSX1 | SSX2 | SSX2IP | SSX3 | SSX4 | SSX5 | SSX6P | SSX7