SQLE: Key Enzyme in Epoxidation Pathway (G6713)

Target Name: SQLE

NCBI ID: G6713

SQLE: Key Enzyme in Epoxidation Pathway

SQLE, or Squalene-2,3-epoxidase, is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the epoxidation pathway, which is a process that involves the oxidation of certain lipids. This pathway is important for the production of various bioactive compounds, including arachidonic acid, which is a pro-inflammatory compound that has been linked to a number of diseases, including heart disease and cancer.

SQLE is a protein that is expressed in various tissues throughout the body, including the liver, heart, and brain. It is a key enzyme in the epoxidation pathway, which is a process that involves the oxidation of certain lipids. This pathway is important for the production of various bioactive compounds, including arachidonic acid, which is a pro-inflammatory compound that has been linked to a number of diseases, including heart disease and cancer.

One of the unique features of SQLE is its ability to epoxidate different types of lipids. This means that it can be used as a drug target or biomarker for a variety of diseases. For example, SQLE has been shown to be involved in the production of arachidonic acid, which is a key precursor to this pro-inflammatory compound. By targeting SQLE, researchers may be able to develop new treatments for a variety of diseases that are related to inflammation.

In addition to its role in the production of arachidonic acid, SQLE is also involved in the regulation of various cellular processes. This includes the production of other compounds that are important for maintaining cellular health and function. For example, SQLE is involved in the production of cell membrane phospholipids, which are important for maintaining the structural integrity of cells. It is also involved in the production of various signaling molecules, including signaling proteins that are involved in cell signaling pathways.

SQLE is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the epoxidation pathway, which is a process that involves the oxidation of certain lipids. This pathway is important for the production of various bioactive compounds, including arachidonic acid, which is a pro-inflammatory compound that has been linked to a number of diseases, including heart disease and cancer. By targeting SQLE, researchers may be able to develop new treatments for a variety of diseases that are related to inflammation.

Protein Name: Squalene Epoxidase

Functions: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis

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