Target Name: SPP2
NCBI ID: G6694
Other Name(s): secreted phosphoprotein 2 | OTTHUMP00000065382 | SPP-24 | secreted phosphoprotein 2, 24kDa | Secreted phosphoprotein 2, 24kDa | Secreted phosphoprotein 2 | Secreted phosphoprotein 24 | Spp-24 | SPP24_HUMAN | SPP24 | secreted phosphoprotein 2, 24kD

SPP2: A Protein Involved in Cell Signaling and Survival

Secreted Phosphoprotein 2 (SPP2) is a protein that is expressed in various cell types of the human body, including neurons, endothelial cells, and epithelial cells. It is a type of transmembrane protein that is characterized by the presence of a phosphatidylinositol (PIP) domain on its extracellular domain and a catalytic domain on its intracellular domain.

SPP2 is involved in various cellular processes that are important for cell survival and function. One of its main functions is to regulate the levels of phosphate groups in cells, which are important for various cellular signaling processes. SPP2 has been shown to play a role in regulating the levels of neurotransmitter release from neurons, and it has been suggested as a potential drug target for various neurological and psychiatric disorders.

SPP2 is also involved in the regulation of cell adhesion and migration. It has been shown to play a role in the regulation of tight junction formation in epithelial cells, which is important for the proper functioning of the skin barrier. SPP2 has also been shown to be involved in the regulation of cell migration, which is important for the development and maintenance of tissues and organs.

SPP2 is also involved in the regulation of cell survival and apoptosis. It has been shown to play a role in the regulation of cell cycle progression, and it has been shown to be involved in the regulation of apoptosis. This suggests that SPP2 may be involved in the development and progression of certain types of cancer.

SPP2 is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of intracellular signaling pathways, including the regulation of neurotransmitter release, cell adhesion, and cell migration. It is also involved in the regulation of cell signaling pathways that are important for cell survival and apoptosis, including the regulation of cell cycle progression and the regulation of apoptosis.

In conclusion, SPP2 is a protein that is involved in a variety of cellular processes that are important for cell survival and function. It is a potential drug target for various neurological and psychiatric disorders, and it may be a useful biomarker for the diagnosis and treatment of certain types of cancer. Further research is needed to fully understand the role of SPP2 in cellular processes and its potential as a drug target.

Protein Name: Secreted Phosphoprotein 2

Functions: Could coordinate an aspect of bone turnover

More Common Targets

SPPL2A | SPPL2B | SPPL2C | SPPL3 | SPR | SPRED1 | SPRED2 | SPRED3 | SPRING1 | SPRN | SPRNP1 | SPRR1A | SPRR1B | SPRR2A | SPRR2B | SPRR2C | SPRR2D | SPRR2E | SPRR2F | SPRR2G | SPRR3 | SPRR4 | SPRTN | SPRY1 | SPRY2 | SPRY3 | SPRY4 | SPRY4-AS1 | SPRY4-IT1 | SPRYD3 | SPRYD4 | SPRYD7 | SPSB1 | SPSB2 | SPSB3 | SPSB4 | SPTA1 | SPTAN1 | SPTB | SPTBN1 | SPTBN2 | SPTBN4 | SPTBN5 | SPTLC1 | SPTLC1P1 | SPTLC2 | SPTLC3 | SPTSSA | SPTSSB | SPTY2D1 | SPX | SPZ1 | SQLE | SQOR | SQSTM1 | SRA1 | SRARP | SRBD1 | SRC | SRCAP | SRCIN1 | SRD5A1 | SRD5A1P1 | SRD5A2 | SRD5A3 | SRD5A3-AS1 | SREBF1 | SREBF2 | SREBF2-AS1 | SREK1 | SREK1IP1 | SRF | SRFBP1 | SRGAP1 | SRGAP2 | SRGAP2B | SRGAP2C | SRGAP2D | SRGAP3 | SRGN | SRI | SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX