SPHKAP: A Protein Regulator of Cellular Processes (G80309)

Target Name: SPHKAP

NCBI ID: G80309

SPHKAP: A Protein Regulator of Cellular Processes

SPHKAP (Small Playbook-related protein K) is a protein that is expressed in various tissues and cells of the human body. It is a key regulator of the cell cycle, and is involved in the development and progression of many diseases, including cancer.

SPHKAP is a member of the MGC family of proteins, which are known for their role in intracellular signaling. MGC proteins are involved in a variety of cellular processes, including cell division, cell signaling, and stress response.

SPHKAP is a 21-kDa protein that is expressed in a variety of tissues and cells, including the brain, spinal cord, heart, and blood vessels. It is highly conserved, with a calculated pI of 6.3.

SPHKAP is involved in the regulation of the cell cycle, and is thought to play a role in the G1/S transition of the cell cycle. This is a critical stage of cell growth and development, and is characterized by increased gene expression and the start of cell division. SPHKAP is involved in the regulation of key events in the G1/S transition, including the transfer of the instruction to the cell cycle protein kinase (CKI), which leads to the start of the S phase.

SPHKAP is also involved in the regulation of the actin cytoskeleton. This is a complex structure that is essential for cell movement and stability. SPHKAP is thought to play a role in the regulation of the actin cytoskeleton by interacting with the protein tyrosine kinase (TK) , which is involved in the regulation of actin dynamics.

SPHKAP is also involved in the regulation of cell signaling. It is a key regulator of the T-cell receptor (TCR), which is a critical molecule involved in the regulation of immune responses. SPHKAP is thought to play a role in the regulation of TCR function by interacting with the protein transcription factor (PTF), which is involved in the regulation of gene expression.

SPHKAP is also involved in the regulation of cell stress response. Stress can damage cells and lead to the development of diseases such as cancer. SPHKAP is thought to play a role in the regulation of cell stress response by interacting with the protein heat shock protein ( Hsp) protein, which is involved in the regulation of stress responses.

SPHKAP is also involved in the regulation of cell migration. This is a critical process that is involved in the development of tissues and organs, as well as the regulation of diseases such as cancer. SPHKAP is thought to play a role in the regulation of cell migration by interacting with the protein cadherin, which is involved in cell-cell adhesion.

In conclusion, SPHKAP is a protein that is involved in a variety of cellular processes and is a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of SPHKAP in cellular processes and its potential as a drug target or biomarker.

Protein Name: SPHK1 Interactor, AKAP Domain Containing

Functions: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1

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