TATDN2: A Key Regulator of TATA-Element-Dependent Gene Expression
TATDN2: A Key Regulator of TATA-Element-Dependent Gene Expression
TATDN2 (TATA-associated protein 2) is a protein that is expressed in various tissues of the human body. It is a key regulator of the TATA-element dependent gene expression, which is a widely recognized mechanism of gene regulation in eukaryotic cells. TATA -element is a core element of the TATA-repeating unit, which is a common feature of gene promoters. The TATA-element is responsible for the regulation of gene expression, and TATDN2 is a known regulator of TATA-element-dependent gene expression.
TATDN2 is a 24.8 kDa protein that is expressed in various tissues of the human body, including muscle, heart, kidney, liver, and brain. It is highly conserved, with a calculated pI of 6.9 and a predicted localization in the cytoplasm. TATDN2 is a monomer and has a linear molecular weight of 10.1 kDa. It has a single transmembrane domain and a N-terminus that is involved in protein-protein interactions.
TATDN2 is a key regulator of TATA-element-dependent gene expression. TATA-element is a core element of the TATA-repeating unit, which is a common feature of gene promoters. The TATA-element is responsible for the regulation of gene expression, and TATDN2 is a known regulator of TATA-element-dependent gene expression. TATDN2 has been shown to interact with various TATA-element-containing proteins, including DNA-binding proteins such as histone-modifying enzymes and histone-remodeling enzymes.
TATDN2 is also involved in the regulation of alternative splicing (AS). Alternative splicing is a process by which the cell removes non-coding exons from the pre-mRNA and uses the remaining exons to generate a functional RNA molecule. TATDN2 has been shown to play a role in the regulation of AS by interacting with the protein SIRP1. SIRP1 is a splicing machinery component that is involved in the regulation of AS.
TATDN2 is also involved in the regulation of cell growth and metabolism. It has been shown to play a role in the regulation of cell cycle progression, cell migration, and cell survival. TATDN2 has been shown to interact with various cell-cycle-related proteins , including the cyclin D1 protein.
TATDN2 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune and inflammatory responses. TATDN2 has been shown to interact with various immune-related proteins, including the transcription factor NF-kappa-B.
TATDN2 is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of various cellular signaling pathways, including the regulation of cell adhesion, the regulation of cell-cell signaling, and the regulation of intracellular signaling pathways. TATDN2 has been shown to interact with various signaling proteins, including the protein kinase PDK4.
TATDN2 is a potential drug target and has been shown to be involved in various cellular processes that are important for human health and disease. It is involved in the regulation of TATA-element-dependent gene expression, which is a common feature of gene promoters. TATDN2 is also involved in the regulation of alternative splicing, cell growth and metabolism, inflammation, and cellular signaling pathways.
In conclusion, TATDN2 is a protein that is involved in various cellular processes that are important for human health and disease. It is a key regulator of TATA-element-dependent gene expression and has been shown to interact with various proteins involved in
Protein Name: TatD DNase Domain Containing 2
Functions: Putative deoxyribonuclease
More Common Targets
TATDN2P3 | TATDN3 | TAX1BP1 | TAX1BP3 | TBATA | TBC1D1 | TBC1D10A | TBC1D10B | TBC1D10C | TBC1D12 | TBC1D13 | TBC1D14 | TBC1D15 | TBC1D16 | TBC1D17 | TBC1D19 | TBC1D2 | TBC1D20 | TBC1D21 | TBC1D22A | TBC1D22A-AS1 | TBC1D22B | TBC1D23 | TBC1D24 | TBC1D25 | TBC1D26 | TBC1D27P | TBC1D28 | TBC1D29P | TBC1D2B | TBC1D3 | TBC1D30 | TBC1D31 | TBC1D32 | TBC1D3B | TBC1D3C | TBC1D3F | TBC1D3G | TBC1D3H | TBC1D3L | TBC1D3P1 | TBC1D3P2 | TBC1D4 | TBC1D5 | TBC1D7 | TBC1D8 | TBC1D8-AS1 | TBC1D8B | TBC1D9 | TBC1D9B | TBCA | TBCB | TBCC | TBCCD1 | TBCD | TBCE | TBCEL | TBCK | TBILA | TBK1 | TBKBP1 | TBL1X | TBL1XR1 | TBL1Y | TBL2 | TBL3 | TBP | TBPL1 | TBPL2 | TBR1 | TBRG1 | TBRG4 | TBX1 | TBX10 | TBX15 | TBX18 | TBX18-AS1 | TBX19 | TBX2 | TBX20 | TBX21 | TBX22 | TBX3 | TBX4 | TBX5 | TBX5-AS1 | TBX6 | TBXA2R | TBXAS1 | TBXT | TC2N | TCAF1 | TCAF1P1 | TCAF2 | TCAIM | TCAM1P | TCAP | TCEA1 | TCEA1P2 | TCEA2