ACC: Enzyme Involved in TCA Cycle and ATP Production (P15278)

Target Name: Acetyl-CoA Carboxylases (ACC)

NCBI ID: P15278

Other Name(s): None

ACC: Enzyme Involved in TCA Cycle and ATP Production

Acetyl-CoA Carboxylases (ACC) are a family of enzymes that are involved in the citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle. These enzymes catalyze the conversion of acetyl-CoA to malate and carbon dioxide, and are crucial for the production of energy in the form of ATP from the TCA cycle.

ACC is a nonspecified subtype, which means that it can catalyze a wide range of different reactions. This subtype is found in many different organisms, including bacteria, archaea, and eukaryotes.

One of the key features of ACC is its catalytic activity on the TCA cycle. This cycle is the central metabolic pathway for most eukaryotes, and is responsible for generating the majority of the energy for the cell. The TCA cycle involves the breakdown of glucose and fatty acids into smaller molecules, such as acetyl-CoA, which is then converted to malate and carbon dioxide.

ACC is the first enzyme in the TCA cycle to convert acetyl-CoA to malate. This conversion is critical for the production of ATP from the TCA cycle. The production of ATP from the TCA cycle is essential for the survival of most organisms, as it provides the energy for the cell's basic functions.

In addition to its role in the TCA cycle, ACC is also involved in the production of other molecules from acetyl-CoA. For example, it can catalyze the conversion of acetyl-CoA to succinyl-CoA, which is involved in the production of succinic acid, a key player in the production of energy in the form of ATP.

ACC is also involved in the regulation of the TCA cycle. This is important for the proper functioning of the cycle and for the production of the correct amount of ATP.

Despite its importance for the TCA cycle, ACC is not a well-studied enzyme. This is because it is a relatively simple enzyme, and as a result, there is not a lot of research focused on its mechanisms of action. However, as more research is done on ACC, it is likely to be found to have a more complex structure and function than previously thought.

In conclusion, Acetyl-CoA Carboxylases (ACC) are a nonspecified subtype that is involved in the TCA cycle and the production of other molecules from acetyl-CoA. While there is not a lot of research on this enzyme, its role in the TCA cycle is critical for the survival of most organisms. As research continues to be done on ACC, it is likely to turn out to be a valuable drug target or biomarker.

Protein Name: Acetyl-CoA Carboxylases (ACC) (nonspecified Subtype)

More Common Targets