Target Name: ANKRD63
NCBI ID: G100131244
Other Name(s): ANR63_HUMAN | Ankyrin repeat domain-containing protein 63 | ankyrin repeat domain 63 | Ankyrin repeat domain 63

ANKRD63: A Potential Drug Target and Biomarker

Ankyrin A gene (ANKRD63) has been identified as a potential drug target and biomarker for several diseases, including cardiovascular disease, neurodegenerative disorders, and diabetes. The ANKRD63 gene is a member of the ANKRD gene family, which is known for its role in the production of angiotensin II, a hormone that contributes to the development of cardiovascular disease.

The ANKRD63 gene has been shown to play a crucial role in the regulation of various physiological processes in the body, including blood pressure, blood flow, and inflammation. Mutations in the ANKRD63 gene have been linked to various cardiovascular diseases, including heart failure, hypertension, and stroke.

In addition to its role in cardiovascular disease, ANKRD63 has also been linked to the development of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells and are associated with significant morbidity and mortality.

The ANKRD63 gene has also been suggested as a potential biomarker for these disorders. The production of ANKRD63 has been shown to be reduced in individuals with Alzheimer's disease and other neurodegenerative disorders. This suggests that ANKRD63 may be a useful diagnostic tool for these conditions.

Furthermore, ANKRD63 has also been shown to play a role in the regulation of inflammation. The ANKRD63 gene has been shown to be involved in the production of pro-inflammatory cytokines, such as TNF-alpha and IL-1. These cytokines contribute to the regulation of immune responses and have been implicated in the development of various inflammatory diseases, including autoimmune disorders and inflammatory bowel disease.

In conclusion, ANKRD63 is a gene that has the potential to be a drug target for various diseases, including cardiovascular disease, neurodegenerative disorders, and diabetes. The ANKRD63 gene has been shown to play a crucial role in the regulation of various physiological processes in the body and has been linked to the development of various cardiovascular and neurodegenerative diseases. Further research is needed to fully understand the role of ANKRD63 in these conditions and to develop effective treatments.

Protein Name: Ankyrin Repeat Domain 63

More Common Targets

ANKRD65 | ANKRD65-AS1 | ANKRD66 | ANKRD7 | ANKRD9 | ANKS1A | ANKS1B | ANKS3 | ANKS4B | ANKS6 | ANKUB1 | ANKZF1 | ANLN | Annexin | ANO1 | ANO10 | ANO2 | ANO3 | ANO4 | ANO5 | ANO6 | ANO7 | ANO7L1 | ANO8 | ANO9 | Anoctamin | ANOS1 | ANOS2P | ANP32A | ANP32A-IT1 | ANP32AP1 | ANP32B | ANP32C | ANP32D | ANP32E | ANPEP | ANTKMT | ANTXR1 | ANTXR2 | ANTXRL | ANTXRLP1 | ANXA1 | ANXA10 | ANXA11 | ANXA13 | ANXA2 | ANXA2P1 | ANXA2P2 | ANXA2P3 | ANXA2R | ANXA2R-AS1 | ANXA2R-OT1 | ANXA3 | ANXA4 | ANXA5 | ANXA6 | ANXA7 | ANXA8 | ANXA8L1 | ANXA8L2 | ANXA9 | AOAH | AOC1 | AOC2 | AOC3 | AOC4P | AOPEP | AOX1 | AOX2P | AP-1 Transcription Factor Complex | AP1AR | AP1B1 | AP1B1P1 | AP1G1 | AP1G2 | AP1M1 | AP1M2 | AP1S1 | AP1S2 | AP1S3 | AP2A1 | AP2A2 | AP2B1 | AP2M1 | AP2S1 | AP3B1 | AP3B2 | AP3D1 | AP3M1 | AP3M2 | AP3S1 | AP3S2 | AP4B1 | AP4B1-AS1 | AP4E1 | AP4M1 | AP4S1 | AP5B1 | AP5M1 | AP5S1