Adenylate Cyclase ADCY1: Key Enzyme in Adenosine Synthesis (G107)

Target Name: ADCY1

NCBI ID: G107

Adenylate Cyclase ADCY1: Key Enzyme in Adenosine Synthesis

Adenylate cyclase (ADCY1) is a gene that encodes a protein involved in the synthesis of adenosine, a molecule that plays a critical role in various physiological processes within the body. ADCY1 is a key enzyme in the adenylate cyclase cascade, a series of reactions that ultimately results in the formation of adenosine.

ADCY1 is expressed in many different tissues throughout the body, including the heart, lungs, kidneys, and intestines. It is primarily localized to the endoplasmic reticulum, where it functions as a transmembrane protein that is involved in the regulation of intracellular signaling pathways.

One of the primary functions of ADCY1 is to catalyze the conversion of the amino acid aspartic acid to the amino acid lysine. This conversion is critical for the synthesis of the nucleotide adenosine, which is then involved in various signaling pathways that regulate cellular processes such as inflammation, stress responses, and cell survival.

ADCY1 is also involved in the regulation of the activity of several other enzymes that are involved in the synthesis of adenosine. For example, it is known to play a role in the regulation of the activity of the enzyme ApoA I, which is involved in the synthesis of low-density lipoprotein (LDL) cholesterol.

In addition to its role in the synthesis of adenosine, ADCY1 is also thought to have several potential drug targets. For example, some studies have suggested that inhibition of ADCY1 may be a potential treatment for various diseases, including heart failure, hypertension, and cancer.

The ability of ADCY1 to participate in the regulation of adenosine synthesis has also led to a focus on the use of adenosine as a potential therapeutic agent. Adenosine has been shown to have a number of potential therapeutic benefits, including the ability to alleviate pain, reduce inflammation, and promote tissue repair.

In conclusion, ADCY1 is a key enzyme involved in the synthesis of adenosine, a molecule that plays a critical role in various physiological processes within the body. Its regulation of adenosine synthesis is the focus of several ongoing research studies, and its potential as a drug target is being actively explored. Further research is needed to fully understand the role of ADCY1 in cellular processes and to develop effective treatments for various diseases.

Protein Name: Adenylate Cyclase 1

Functions: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels (By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity)

More Common Targets