ADPRH: A Potential Drug Target and Biomarker (G141)

Target Name: ADPRH

NCBI ID: G141

ADPRH: A Potential Drug Target and Biomarker

ADP-ribosylhydrolase (ADPRH) is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the repair and maintenance of RNA stability, and is highly conserved across different species. ADPRH is also known as ARH1, and is a potential drug target and biomarker.

ADPRH is a protein that is composed of 256 amino acids. It has a molecular weight of 31 kDa, and a pre-steady state activity of 13.9 kDa. ADPRH is highly conserved across different species, and is found in various organisms, including bacteria, archaea, and eukaryotes.

ADPRH is involved in the repair and maintenance of RNA stability. RNA is a critical molecule in the cell, and is responsible for carrying genetic information from the DNA to the ribosome, where it is translated into proteins. ADPRH is involved in the post-transcriptional modification of RNA, which is a critical step in the regulation of gene expression.

ADPRH is also involved in the degradation of damaged RNA. Damaged RNA can no longer be translated into proteins, and can be either degraded or translated into a functional RNA. ADPRH is involved in the degradation of damaged RNA by the ubiquitin-proteasome system.

ADPRH is a potential drug target because of its role in the regulation of RNA stability. By targeting ADPRH, researchers may be able to manipulate RNA stability and improve the translation of RNA into proteins. This could lead to a variety of therapeutic benefits, including the treatment of diseases such as cancer, where the regulation of RNA stability is disrupted.

ADPRH is also a potential biomarker for certain diseases. The expression of ADPRH has been detected in a variety of tissues and conditions, including cancer, neurodegenerative diseases, and RNA-related diseases. By measuring the expression of ADPRH, researchers may be able to diagnose and monitor the progression of these diseases.

In conclusion, ADP-ribosylhydrolase (ADPRH) is a protein that is involved in the repair and maintenance of RNA stability. It is a potential drug target and biomarker, and its study may have a variety of therapeutic and diagnostic implications. Further research is needed to fully understand the role of ADPRH in the regulation of RNA stability and its potential as a drug target and biomarker.

Protein Name: ADP-ribosylarginine Hydrolase

Functions: Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins

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