AGT: A Drug Target / Disease Biomarker (G183)
AGT: A Drug Target / Disease Biomarker
AGT, or Angiotensin-converting enzyme, is a protein that is expressed in various tissues throughout the body, including the heart, kidneys, lungs, and intestines. It plays a crucial role in regulating the body's blood pressure by breaking down a hormone called angiotensin II, which can cause blood vessels to constrict and raise blood pressure.
AGT has also been shown to have a number of potential drug targets and biomarkers. One of these targets is the protein called FAK, which is a key regulator of cell signaling and has been implicated in a number of diseases, including cancer.
Research has also shown that AGT can be used as a biomarker for a number of conditions, including heart failure, chronic kidney disease, and liver disease. These biomarkers can be used to diagnose and monitor these conditions, which can be life-threatening and are often difficult to diagnose.
In addition to its potential drug and biomarker applications, AGT has also been shown to have a number of potential therapeutic applications. For example, it has been shown to be involved in the regulation of inflammation, which can contribute to a number of diseases, including heart disease and cancer.
Furthermore, AGT has also been shown to have a number of potential applications in regenerative medicine. For example, it has been used to stimulate the growth of stem cells and has been shown to be effective in repairing damaged tissue in animal models.
Overall, AGT is a protein that has a number of potential applications in a variety of fields, including medicine and regenerative science. Further research is needed to fully understand its role and potential as a drug target and biomarker.
Protein Name: Angiotensinogen
Functions: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis
More Common Targets
AGTPBP1 | AGTR1 | AGTR2 | AGTRAP | AGXT | AGXT2 | AHCTF1 | AHCTF1P1 | AHCY | AHCYL1 | AHCYL2 | AHCYP1 | AHCYP2 | AHDC1 | AHI1 | AHI1-DT | AHNAK | AHNAK2 | AHR | AHRR | AHSA1 | AHSA2P | AHSG | AHSP | AICDA | AIDA | AIDAP1 | AIF1 | AIF1L | AIFM1 | AIFM2 | AIFM3 | AIG1 | AIM2 | AIM2 Inflammasome | AIMP1 | AIMP2 | AIP | AIPL1 | AIRE | AJAP1 | AJM1 | AJUBA | AK1 | AK2 | AK2P2 | AK4 | AK4P1 | AK4P6 | AK5 | AK6 | AK6P1 | AK7 | AK8 | AK9 | AKAIN1 | AKAP1 | AKAP10 | AKAP11 | AKAP12 | AKAP13 | AKAP14 | AKAP17A | AKAP2 | AKAP3 | AKAP4 | AKAP5 | AKAP6 | AKAP7 | AKAP8 | AKAP8L | AKAP9 | AKIP1 | AKIRIN1 | AKIRIN2 | AKNA | AKNAD1 | AKR1A1 | AKR1B1 | AKR1B10 | AKR1B10P1 | AKR1B15 | AKR1C1 | AKR1C2 | AKR1C3 | AKR1C4 | AKR1C6P | AKR1C8 | AKR1D1 | AKR1E2 | AKR7A2 | AKR7A2P1 | AKR7A3 | AKR7L | AKT1 | AKT1S1 | AKT2 | AKT3 | AKTIP | ALAD