AK9: A Protein with Potential as A Drug Target Or Biomarker (G221264)

Target Name: AK9

NCBI ID: G221264

AK9: A Protein with Potential as A Drug Target Or Biomarker

AK9 (Adenylate kinase 9) is a protein that is expressed in various tissues throughout the body, including muscle, heart, and brain. It plays a crucial role in the regulation of cellular signaling pathways, and its function has been extensively studied over the years. In this article, we will discuss the research on AK9 and its potential as a drug target or biomarker.

History of AK9 Research

The study of AK9 began in the 1970s, when researchers identified the protein as a potential receptor for the neurotransmitter acetylcholine. Since then, numerous studies have confirmed its role in various cellular processes, including neurotransmission, muscle physiology, and cardiac function.

One of the most significant findings of AK9 research was its role in neurotransmission. Studies have shown that AK9 is involved in the uptake and storage of neurotransmitters, including acetylcholine, a potent neurotransmitter that modulates memory and learning.

In addition to its role in neurotransmission, AK9 has also been shown to be involved in the regulation of muscle physiology. Studies have shown that AK9 plays a role in the regulation of muscle contractions and muscle relaxation.

Moreover, AK9 has also been shown to be involved in cardiac function. Studies have shown that AK9 is involved in the regulation of cardiac contractions and heart rate.

Potential Therapeutic Applications

The potential therapeutic applications of AK9 are vast, and numerous studies have suggested that it may be a useful drug target or biomarker. One of the most promising applications of AK9 is its potential as a neurotransmitter receptor antagonist.

Neurotransmitter receptors are the target of many drugs used to treat various psychiatric and neurological disorders. However, these drugs often have limited efficacy and can cause potential side effects. By blocking AK9, researchers may be able to develop more effective treatments for neurotransmission disorders.

In addition to its potential as a neurotransmitter receptor antagonist, AK9 has also been shown to be a potential biomarker for various diseases. For example, studies have shown thatAK9 levels are elevated in the brains of individuals with Alzheimer's disease, and that inhibiting AK9 activity may be a promising approach to treating this disease.

Another promising application of AK9 is its potential as a target for cancer therapy. Studies have shown that AK9 is involved in the regulation of cellular signaling pathways, and that inhibiting its activity may be a promising approach to cancer treatment.

Conclusion

In conclusion, AK9 is a protein that has been extensively studied over the years for its role in cellular signaling pathways. Its function as a neurotransmitter receptor and its potential as a drug target or biomarker make it an attractive target for further research. As research continues, we may find new and innovative ways to use AK9 for the treatment of various diseases.

Protein Name: Adenylate Kinase 9

Functions: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP

More Common Targets