SEPTIN9: A Potential Drug Target and Biomarker (G10801)

Target Name: SEPTIN9

NCBI ID: G10801

SEPTIN9: A Potential Drug Target and Biomarker

SEPTIN9 is a protein that plays a crucial role in the structure and function of hair shafts. It is a member of the SEPIN family, which is known for their ability to interact with various signaling pathways, including TGF-β and Wnt. SEPTIN9 has been shown to be involved in the regulation of cell proliferation, differentiation, and survival.

SEPTIN9 has also been implicated in the development and progression of various diseases, including cancer. For example, studies have shown that SEPTIN9 levels are decreased in various types of cancer, and that inhibition of SEPTIN9 has been shown to have therapeutic benefits in these diseases.

Due to its involvement in these processes, SEPTIN9 has potential as a drug target. By targeting SEPTIN9 with small molecules or other compounds, researchers may be able to inhibit its activity and potentially treat various diseases.

In addition to its potential as a drug target, SEPTIN9 has also been identified as a potential biomarker. The SEPIN family has been shown to be involved in the regulation of various signaling pathways, including TGF-β and Wnt. This suggests that SEPTIN9 may be involved in the regulation of these processes, and that its levels or activity may be relevant to the diagnosis or progression of certain diseases.

To further explore the potential of SEPTIN9 as a biomarker, researchers have conducted studies to determine if it can be used as a diagnostic marker for certain diseases. For example, studies have shown that SEPTIN9 levels are decreased in various types of cancer, including breast, ovarian, and prostate cancer. This suggests that SEPTIN9 may be a useful biomarker for the diagnosis and progression of these diseases.

In addition, SEPTIN9 has also been shown to be involved in the regulation of cell survival and proliferation. This suggests that it may be involved in the development and progression of certain diseases, such as neurodegenerative disorders.

Overall, SEPTIN9 has a strong potential as a drug target and biomarker. Its involvement in various signaling pathways and its association with the development and progression of various diseases make it an attractive target for researchers to investigate further. Further studies are needed to fully understand its potential and to determine its utility as a drug and biomarker.

Protein Name: Septin 9

Functions: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri

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