Target Name: SERPINB8
NCBI ID: G5271
Other Name(s): CAP2 | Serpin family B member 8, transcript variant 2 | protease inhibitor 8 (ovalbumin type) | cytoplasmic antiproteinase 2 | C18orf53 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | CAP-2 | Proteinase inhibitor 8 | PI-8 | SERPINB8 variant 2 | Protease inhibitor 8 (ovalbumin type) | Peptidase inhibitor 8 | PSS5 | serpin family B member 8 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 | SPB8_HUMAN | peptidase inhibitor 8 | Cytoplasmic antiproteinase 2 | Serpin B8 | PI8 | serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8

Serpinb8 (CAP2): A novel Drug Target and Biomarker for the Treatment of Fibrosis and other Chronic Diseases

Abstract:

Serpinb8 (CAP2) is a protein that is expressed in various tissues and cells throughout the body. Its functions include but are not limited to modulating the extracellular matrix (ECM), regulating the growth and differentiation of tissues, and playing a role in the development and progression of various diseases, including fibrosis. In this article, we will discuss the role of Serpinb8 (CAP2) as a drug target and biomarker, with a focus on its potential therapeutic applications in the treatment of fibrosis and other chronic diseases.

Introduction:

Fibrosis is a complex pathological process that involves the progressive accumulation of extracellular matrix (ECM) components, leading to the loss of tissue function and quality of life. Fibrosis can occur in various tissues, including but not limited to lungs, hearts, kidneys, livers, andAddress:

Protein Name: Serpin Family B Member 8

Functions: Has an important role in epithelial desmosome-mediated cell-cell adhesion

More Common Targets

SERPINB9 | SERPINB9-AS1 | SERPINB9P1 | SERPINC1 | SERPIND1 | SERPINE1 | SERPINE2 | SERPINE3 | SERPINF1 | SERPINF2 | SERPING1 | SERPINH1 | SERPINI1 | SERPINI2 | SERTAD1 | SERTAD2 | SERTAD3 | SERTAD4 | SERTAD4-AS1 | SERTM1 | SERTM2 | Serum amyloid protein | SESN1 | SESN2 | SESN3 | SESTD1 | Sestrin | SET | SET1 histone methyltransferase complex | SETBP1 | SETBP1-DT | SETD1A | SETD1B | SETD2 | SETD3 | SETD4 | SETD4-AS1 | SETD5 | SETD6 | SETD7 | SETD9 | SETDB1 | SETDB2 | SETMAR | SETP14 | SETP20 | SETP22 | SETX | SEZ6 | SEZ6L | SEZ6L2 | SF1 | SF3A1 | SF3A2 | SF3A3 | SF3A3P2 | SF3B1 | SF3B2 | SF3B3 | SF3B4 | SF3B5 | SF3B6 | SFI1 | SFMBT1 | SFMBT2 | SFN | SFPQ | SFR1 | SFRP1 | SFRP2 | SFRP4 | SFRP5 | SFSWAP | SFT2D1 | SFT2D2 | SFT2D3 | SFTA1P | SFTA2 | SFTA3 | SFTPA1 | SFTPA2 | SFTPB | SFTPC | SFTPD | SFXN1 | SFXN2 | SFXN3 | SFXN4 | SFXN5 | SGCA | SGCB | SGCD | SGCE | SGCG | SGCZ | SGF29 | SGIP1 | SGK1 | SGK2 | SGK3