SGCE: A Protein Involved in Synapse Development and Neurotransmission

Target Name: SGCE

NCBI ID: G8910

SGCE: A Protein Involved in Synapse Development and Neurotransmission

SGCE (SGCE variant 3) is a protein that is expressed in the brain and is involved in the development and maintenance of synapses, which are the structural and functional connections between neurons in the nervous system. SGCE has been identified as a potential drug target for the treatment of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions.

SGCE is a transmembrane protein that is composed of four domains: an extracellular domain, a transmembrane domain, an intracellular domain, and a C-terminal domain. The extracellular domain is responsible for SGCE's ability to interact with other proteins and molecules, while the transmembrane domain is responsible for SGCE's ability to span the cell membrane and interact with intracellular signaling pathways. The intracellular domain is responsible for SGCE's ability to interact with and modulate the activity of various signaling pathways within cells, while the C-terminal domain is responsible for SGCE's ability to interact with and modulate the activity of other proteins.

SGCE has been shown to play a role in the development and maintenance of synapses, which are the structural and functional connections between neurons in the nervous system. Synapses are critical for the transmission of electrical signals between neurons and are involved in the regulation of a wide range of physiological processes, including learning and memory. SGCE has been shown to be involved in the formation and maintenance of synapses by regulating the activity of various signaling pathways, including the tyrosine kinase pathway and the Wnt pathway.

SGCE has also been shown to be involved in the regulation of neurotransmitter release from neurons. Neurotransmitters are chemical messengers that are used by neurons to communicate with other neurons and with the endostrium, which is the lining of the blood vessels in the brain. SGCE has been shown to regulate the release of neurotransmitters from neurons by modulating the activity of various signaling pathways, including the neurotransmitter release pathway and the voltage-gated ion channel (VGCC) pathway.

In addition to its role in the regulation of synapses and neurotransmitter release, SGCE has also been shown to be involved in the regulation of cellular processes such as cell adhesion, migration, and survival. SGCE has been shown to play a role in the regulation of cell adhesion by modulating the activity of various signaling pathways, including the cadherin/cathelin system and the tight junction protein (TJP). SGCE has also been shown to play a role in the regulation of cell migration by modulating the activity of various signaling pathways, including the sonic hedgehog pathway and the Wnt pathway. SGCE has also been shown to play a role in the regulation of cellular survival by modulating the activity of various signaling pathways, including the apoptosis pathway.

SGCE has also been shown to be involved in the regulation of behavioral processes such as learning and memory. SGCE has been shown to play a role in the regulation of learning and memory by modulating the activity of various signaling pathways, including the consolidation of memories pathway and the neurotransmitter release pathway.

Overall, SGCE is a protein that is involved in the development and maintenance of synapses, as well as the regulation of various physiological processes including neurotransmission, cell adhesion, migration, and survival. As a result, SGCE has been identified as a potential drug target for the treatment of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions. Further research is needed to fully understand the role of SGCE in the regulation of nervous system function and to develop effective treatments for SGCE-related disorders.

Protein Name: Sarcoglycan Epsilon

Functions: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix

More Common Targets