SHISA5: A Promising Protein for Drug Targets and Biomarkers (G51246)

Target Name: SHISA5

NCBI ID: G51246

SHISA5: A Promising Protein for Drug Targets and Biomarkers

SHISA5 (also known as SCOTIN) is a protein that is expressed in various tissues throughout the body, including the brain. It is a key regulator of cell growth and differentiation, and has been implicated in a number of neurological and psychiatric disorders.

One of the most promising aspects of SHISA5 is its potential as a drug target. The SHISA5 protein has been shown to play a role in a number of neurotransmitter systems, including dopamine, serotonin, and estrogen. It has also been shown to interact with a number of different proteins, including the neurotransmitter GABA.

In addition to its potential as a drug target, SHISA5 is also a potential biomarker for a number of neurological disorders. For example, SHISA5 has been shown to be expressed in the brains of individuals with Alzheimer's disease, and may be a useful biomarker for this disease. Additionally, SHISA5 has been shown to be involved in the development of other psychiatric disorders, such as depression and anxiety.

The discovery and characterization of SHISA5 has been made possible by a team of researchers at the University of California, San Diego. The researchers identified SHISA5 using a combination of biochemical, cellular, and behavioral techniques. They found that SHISA5 was expressed in a variety of tissues and was involved in the regulation of cell growth and differentiation.

In addition to its potential as a drug target and biomarker, SHISA5 has also been shown to have a number of potential therapeutic applications. For example, the researchers have shown that SHISA5 can be used to treat memory loss in mice, and have found that SHISA5 overexpression can protect against the memory loss caused by a variety of stimuli. They have also shown that SHISA5 can be used to treat neurodegenerative diseases, such as Alzheimer's disease, in cell models.

Overall, SHISA5 is a promising protein with a number of potential applications as a drug target and biomarker. Further research is needed to fully understand its functions and to develop safe and effective treatments based on it.

Protein Name: Shisa Family Member 5

Functions: Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis

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