SIRPD: A Protein Targeted for Drug Development (G128646)
SIRPD: A Protein Targeted for Drug Development
SIRPD (Protein Tyrosine Phosphatase Non-Receptor Type Substrate 1-Like 2) is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the signal transduction pathway, which is responsible for regulating various cellular processes. SIRPD has has been identified as a potential drug target and has been shown to be involved in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
SIRPD is a protein that is characterized by its unique structure and mechanism of action. It is a serine protein that consists of 218 amino acids. It has a catalytic active site that is located at the N-terminus of the protein. is composed of a positively charged residue, a negatively charged residue, and a hydrophobic amino acid. This site is the site of the protein's catalytic activity and is responsible for the chemical reaction that is the rate-limiting step in the signal transduction pathway.
SIRPD is involved in the regulation of various cellular processes, including cell signaling, cell growth, and cell death. It is a key enzyme in the PI3K/Akt signaling pathway, which is responsible for regulating the growth and survival of various cell types. is also involved in the regulation of the NF-kappa-B signaling pathway, which is responsible for regulating inflammation and cellular responses to stress.
SIRPD has been shown to be involved in various diseases and conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that high levels of SIRPD are associated with an increased risk of cancer, including breast, ovarian, and prostate cancer. Additionally, SIRPD has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.
SIRPD has also been shown to be involved in the regulation of cellular responses to stress, including inflammation and cellular death. For example, studies have shown that SIRPD is involved in the regulation of the inflammatory response to stress, including the production of pro-inflammatory cytokines. Additionally, SIRPD has been shown to be involved in the regulation of cellular responses to stress, including the production of neurotransmitters that regulate cellular death.
In conclusion, SIRPD is a protein that is involved in the regulation of various cellular processes and has been identified as a potential drug target. Its unique structure and mechanism of action, as well as its involvement in the PI3K/Akt and NF-kappa-B signaling pathways, make it an attractive target for drug development. Further research is needed to fully understand the role of SIRPD in the regulation of cellular processes and to develop effective therapies that target this protein.
Protein Name: Signal Regulatory Protein Delta
More Common Targets
SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1 | SKA1 complex | SKA2 | SKA2P1 | SKA3 | SKAP1 | SKAP1-AS2 | SKAP2 | Skeletal muscle troponin | SKI | SKIC2 | SKIC3 | SKIC8 | SKIDA1 | SKIL | SKINT1L | SKOR1 | SKOR2 | SKP1 | SKP1P2 | SKP2 | SLA | SLA2 | SLAIN1 | SLAIN2 | SLAM Family Member | SLAMF1 | SLAMF6 | SLAMF6P1 | SLAMF7 | SLAMF8 | SLAMF9 | SLBP | SLC corepressor complex | SLC10A1 | SLC10A2 | SLC10A3 | SLC10A4 | SLC10A5 | SLC10A6 | SLC10A7 | SLC11A1 | SLC11A2 | SLC12A1 | SLC12A2 | SLC12A2-DT | SLC12A3 | SLC12A4 | SLC12A5 | SLC12A5-AS1 | SLC12A6 | SLC12A7 | SLC12A8 | SLC12A9 | SLC13A1 | SLC13A2 | SLC13A3 | SLC13A4 | SLC13A5 | SLC14A1 | SLC14A2 | SLC15A1 | SLC15A2 | SLC15A3 | SLC15A4 | SLC15A5 | SLC16A1 | SLC16A10 | SLC16A11 | SLC16A12 | SLC16A13 | SLC16A14 | SLC16A2 | SLC16A3 | SLC16A4 | SLC16A5 | SLC16A6 | SLC16A6P1 | SLC16A7 | SLC16A8 | SLC16A9 | SLC17A1