SLC12A7: A Potential Drug Target and Biomarker (G10723)

Target Name: SLC12A7

NCBI ID: G10723

SLC12A7: A Potential Drug Target and Biomarker

Solute Carrier Family 12 (SLC12) is a family of transmembrane proteins that play a crucial role in the transport of various molecules across cell membranes. The SLC12 family consists of 12 different proteins, including SLC12A7, which is a member of this family. SLC12A7 is a 7-kDa protein that is expressed in various tissues and organs, including brain, heart, liver, and kidney.

SLC12A7 is a protein that is involved in the transport of several different molecules, including glucose, amino acids, and nucleotides. It is a member of the SLC12 family, which is characterized by the presence of a transmembrane segment and a cytoplasmic tail. SLC12A7 functions as a carrier protein, allowing molecules to pass through the cell membrane and into the cytoplasm.

SLC12A7 has been identified as a potential drug target due to its involvement in the transport of various molecules across cell membranes. The ability of SLC12A7 to transport different molecules makes it an attractive target for drug development because it can be targeted directly with small molecules. Additionally, SLC12A7 is a cytoplasmic protein, which means that it is located within the cytoplasm of the cell. This is important because drugs that target membrane-bound proteins have a limited impact on cytoplasmic proteins, which are the majority of proteins in the cytoplasm.

SLC12A7 has also been identified as a potential biomarker for several diseases, including diabetes, heart disease, and neurodegenerative diseases. The ability of SLC12A7 to transport glucose and other molecules across cell membranes makes it an attractive target for the development of drugs for these diseases.

SLC12A7 has been shown to be involved in several cellular processes that are important for the health and function of cells. For example, SLC12A7 is involved in the uptake and processing of glucose, which is essential for the survival of cells. Additionally, SLC12A7 is involved in the transport of amino acids, which are essential for the growth and maintenance of cells.

SLC12A7 is also involved in the regulation of several cellular processes that are important for the health and function of cells. For example, SLC12A7 is involved in the regulation of cell adhesion, which is important for the formation of tissues and organs. Additionally, SLC12A7 is involved in the regulation of cell survival, which is important for the maintenance of tissue homeostasis.

SLC12A7 is also involved in several signaling pathways that are important for the health and function of cells. For example, SLC12A7 is involved in theInsulin-like growth factor (IGF) signaling pathway, which is important for the growth and maintenance of cells. Additionally, SLC12A7 is involved in the TGF-β signaling pathway, which is important for the regulation of cell growth and differentiation.

SLC12A7 is a protein that is involved in the transport of various molecules across cell membranes. Its involvement in the transport of glucose, amino acids, and nucleotides makes it an attractive target for drug development. Additionally, SLC12A7 is a cytoplasmic protein, which makes it an attractive target for drugs that target membrane-bound proteins. Further research is needed to fully understand the role of SLC12A7 in cellular processes and to develop effective drugs that target this protein.

Protein Name: Solute Carrier Family 12 Member 7

Functions: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:10913127). May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity)

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